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Table 3 Predictors of mortality in patients with ischemic and haemorrhagic stroke during a 30-day and 90-day follow up in Kampala, Uganda

From: Predictors of 30-day and 90-day mortality among hemorrhagic and ischemic stroke patients in urban Uganda: a prospective hospital-based cohort study

 

30 -day mortality

90 -day mortality

Variable

uHR (95% CI)

LRT

p-value

aHR (95%CI)

uHR (95% CI)

LRT

p-value

aHR (95%CI)

Age (years)

 

0.032

  

0.044

 

  < 60

1

 

1

  

1

  ≥ 60

2.30 (1.03–5.14)

 

1.11 (0.45–2.75)

1.95 (1.02–3.73)

0.092

0.92 (0.41–2.06)

Gender, male

0.41 (0.17–0.98)

0.031

0.54 (0.20–1.46)

0.57 (0.29–1.13)

 

0.78 (0.32–1.90)

Marital status

 

0.222

  

0.063

 

 -Never married

1

  

1

 

1

 -Widowed

2.79 (0.36–21.3)

  

0.71 (0.24–2.14)

 

0.26 (0.07–1.01)

 -Divorced/separated

3.89 (0.47–32.2)

  

1.42 (0.44–4.54)

 

0.32 (0.07–1.43)

 -Married

1.59 (0.21–12.3)

  

0.46 (0.15–1.40)

 

0.22 (0.06–0.84)

Education level

 

0.395

  

0.824

 

 -No education

1

  

1

  

 -Primary

0.52 (0.18–1.46)

  

0.92 (0.36–2.34)

  

 -Secondary & above

0.81 (0.32–2.07)

  

1.12 (0.45–2.76)

  

Smoking

 

0.009

  

0.105

 

 No

1

 

1

1

 

1

 Yes

4.64 (1.11–19.4)

 

3.85 (0.88–16.8)

1.96 (0.82–4.59)

 

1.68 (0.69–4.11)

BP ≥ 140/90

 

0.288

  

0.267

 

 - No

1

  

1

  

 - Yes

1.49 (0.70–3.17)

  

1.42 (0.75–2.69)

  

Obese

 

0.764

  

0.357

 

 - No

1

  

1

  

 - Yes

0.87 (0.36–2.13)

  

0.69 (0.31–1.56)

  

-HIV infection

 

0.270

  

0.749

 

 - No

1

  

1

  

 - Yes

0.58 (0.20–1.64)

  

0.88 (0.41–1.90)

  

-Length of hospital stay

 

0.040

  

0.017

 

 - < 7 days

1

 

1

1

 

1

 -7–13 days

0.58 (0.21–1.60)

 

0.31 (0.11–0.93)

1.03 (0.50–2.15)

 

0.55 (0.24–1.26)

 -14–29 days

2.64 (1.17–6.00)

 

1.02 (0.37–2.81)

3.22 (1.53–6.78)

 

1.10 (0.42–2.82)

 - ≥ 30 days

0.58 (0.08–4.36)

 

0.20 (0.02–1.71)

0.43 (0.06–3.18)

 

0.13 (0.02–1.06)

Glasgow Coma Scale

 

< 0.001

  

< 0.001

 

 - ≥ 9

1

 

1

1

 

1

 - < 9

4.71 (2.24–9.87)

 

3.49 (1.39–8.75)

4.33 (2.24–8.36)

 

4.34 (1.85–10.2)

Stroke severity at enrolment

 

< 0.001

  

< 0.001

 

 -NIHSS 0–12

1

 

1

1

 

1

 -NIHSS 13–20

2.71 (0.91–8.05)

 

1.48 (0.45–4.91)

2.24 (0.95–5.27)

 

1.85 (0.68–5.03)

 -NIHSS ≥21

5.89 (2.33–14.8)

 

2.73 (0.85–8.80)

4.66 (2.26–9.58)

 

2.63 (1.68–10.5)

Pre-stroke functional status

 

0.998

  

0.798

 

 -mRS 0–2a

1

 

1

1

 

1

 -mRS 3

0.95 (0.13–7.00)

 

0.29 (0.03–2.84)

1.35 (0.33–5.60)

 

0.36 (0.07–1.79)

 -mRS 4–5

1.03 (0.14–7.59)

 

0.37 (0.03–4.51)

0.61 (0.08–4.46)

 

0.40 (0.04–3.71)

Stroke type

 

0.089

  

0.133

 

 Ischemic strokea

1

 

1

1

 

1

 Haemorrhagic stroke

1.86 (0.92–3.76)

 

1.95 (0.90–4.25)

1.59 (0.88–2.89)

 

2.30 (1.13–4.66)

Functional status at enrolment

 

0.006

  

0.004

 

 -mRS 0–3a

1

     

 -mRS 4–5

4.89 (1.17–20.5)

 

2.55 (0.52–12.6)

3.58 (1.28–10.0)

 

2.15 (0.66–7.08)

  1. a reference category; uHR unadjusted hazard ratios, aOR adjusted hazard ratios, CI Confidence interval, BP Blood pressure, LRT likelihood ratio test, NIHSS National Institute of Health Stroke Scale, mRS Modified Rankin Scale
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