| 30 -day mortality | 90 -day mortality | ||||
---|---|---|---|---|---|---|
Variable | uHR (95% CI) | LRT p-value | aHR (95%CI) | uHR (95% CI) | LRT p-value | aHR (95%CI) |
Age (years) | Â | 0.032 | Â | Â | 0.044 | Â |
  < 60 | 1 |  | 1 |  |  | 1 |
  ≥ 60 | 2.30 (1.03–5.14) |  | 1.11 (0.45–2.75) | 1.95 (1.02–3.73) | 0.092 | 0.92 (0.41–2.06) |
Gender, male | 0.41 (0.17–0.98) | 0.031 | 0.54 (0.20–1.46) | 0.57 (0.29–1.13) |  | 0.78 (0.32–1.90) |
Marital status | Â | 0.222 | Â | Â | 0.063 | Â |
 -Never married | 1 |  |  | 1 |  | 1 |
 -Widowed | 2.79 (0.36–21.3) |  |  | 0.71 (0.24–2.14) |  | 0.26 (0.07–1.01) |
 -Divorced/separated | 3.89 (0.47–32.2) |  |  | 1.42 (0.44–4.54) |  | 0.32 (0.07–1.43) |
 -Married | 1.59 (0.21–12.3) |  |  | 0.46 (0.15–1.40) |  | 0.22 (0.06–0.84) |
Education level | Â | 0.395 | Â | Â | 0.824 | Â |
 -No education | 1 |  |  | 1 |  |  |
 -Primary | 0.52 (0.18–1.46) |  |  | 0.92 (0.36–2.34) |  |  |
 -Secondary & above | 0.81 (0.32–2.07) |  |  | 1.12 (0.45–2.76) |  |  |
Smoking | Â | 0.009 | Â | Â | 0.105 | Â |
 No | 1 |  | 1 | 1 |  | 1 |
 Yes | 4.64 (1.11–19.4) |  | 3.85 (0.88–16.8) | 1.96 (0.82–4.59) |  | 1.68 (0.69–4.11) |
BP ≥ 140/90 |  | 0.288 |  |  | 0.267 |  |
 - No | 1 |  |  | 1 |  |  |
 - Yes | 1.49 (0.70–3.17) |  |  | 1.42 (0.75–2.69) |  |  |
Obese | Â | 0.764 | Â | Â | 0.357 | Â |
 - No | 1 |  |  | 1 |  |  |
 - Yes | 0.87 (0.36–2.13) |  |  | 0.69 (0.31–1.56) |  |  |
-HIV infection | Â | 0.270 | Â | Â | 0.749 | Â |
 - No | 1 |  |  | 1 |  |  |
 - Yes | 0.58 (0.20–1.64) |  |  | 0.88 (0.41–1.90) |  |  |
-Length of hospital stay | Â | 0.040 | Â | Â | 0.017 | Â |
 - < 7 days | 1 |  | 1 | 1 |  | 1 |
 -7–13 days | 0.58 (0.21–1.60) |  | 0.31 (0.11–0.93) | 1.03 (0.50–2.15) |  | 0.55 (0.24–1.26) |
 -14–29 days | 2.64 (1.17–6.00) |  | 1.02 (0.37–2.81) | 3.22 (1.53–6.78) |  | 1.10 (0.42–2.82) |
 - ≥ 30 days | 0.58 (0.08–4.36) |  | 0.20 (0.02–1.71) | 0.43 (0.06–3.18) |  | 0.13 (0.02–1.06) |
Glasgow Coma Scale |  | < 0.001 |  |  | < 0.001 |  |
 - ≥ 9 | 1 |  | 1 | 1 |  | 1 |
 - < 9 | 4.71 (2.24–9.87) |  | 3.49 (1.39–8.75) | 4.33 (2.24–8.36) |  | 4.34 (1.85–10.2) |
Stroke severity at enrolment |  | < 0.001 |  |  | < 0.001 |  |
 -NIHSS 0–12 | 1 |  | 1 | 1 |  | 1 |
 -NIHSS 13–20 | 2.71 (0.91–8.05) |  | 1.48 (0.45–4.91) | 2.24 (0.95–5.27) |  | 1.85 (0.68–5.03) |
 -NIHSS ≥21 | 5.89 (2.33–14.8) |  | 2.73 (0.85–8.80) | 4.66 (2.26–9.58) |  | 2.63 (1.68–10.5) |
Pre-stroke functional status | Â | 0.998 | Â | Â | 0.798 | Â |
 -mRS 0–2a | 1 |  | 1 | 1 |  | 1 |
 -mRS 3 | 0.95 (0.13–7.00) |  | 0.29 (0.03–2.84) | 1.35 (0.33–5.60) |  | 0.36 (0.07–1.79) |
 -mRS 4–5 | 1.03 (0.14–7.59) |  | 0.37 (0.03–4.51) | 0.61 (0.08–4.46) |  | 0.40 (0.04–3.71) |
Stroke type | Â | 0.089 | Â | Â | 0.133 | Â |
 Ischemic strokea | 1 |  | 1 | 1 |  | 1 |
 Haemorrhagic stroke | 1.86 (0.92–3.76) |  | 1.95 (0.90–4.25) | 1.59 (0.88–2.89) |  | 2.30 (1.13–4.66) |
Functional status at enrolment | Â | 0.006 | Â | Â | 0.004 | Â |
 -mRS 0–3a | 1 |  |  |  |  |  |
 -mRS 4–5 | 4.89 (1.17–20.5) |  | 2.55 (0.52–12.6) | 3.58 (1.28–10.0) |  | 2.15 (0.66–7.08) |