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Table 1 Baseline characteristics, echocardiographic data and outcomes in all patients and the comparisons between patients with significant and insignificant functional tricuspid regurgitation

From: Significant functional tricuspid regurgitation portends poor outcomes in patients with atrial fibrillation and preserved left ventricular ejection fraction

Variables All patients (n = 300) Significant FTR (n = 65) Insignificant FTR (n = 235) P-value
Baseline characteristics
 Age (years) 68.8 ± 10.8 71.3 ± 10.3 68.1 ± 10.9 0.034
 Female gender 150 (50.0) 45 (68.2) 105 (44.7) <  0.001
 Non-paroxysmal AF 196 (65.3) 53 (81.5) 143 (60.9) 0.010
 CHA2DS2-VASc score 3.3 ± 1.7 3.6 ± 1.8 3.2 ± 1.7 0.103
 Hypertension 235 (78.3) 50 (76.9) 185 (79.1) 0.710
 Dyslipidemia 153 (51.0) 24 (36.9) 129 (54.9) 0.010
 Diabetes mellitus 105 (35.0) 17 (26.2) 88 (37.4) 0.091
 History of stroke 88 (29.3) 18 (28.1) 70 (29.8) 0.796
 History of heart failure 45 (15.0) 11 (16.9) 34 (14.5) 0.624
 Diuretics 58 (19.3) 20 (30.8) 38 (16.2) 0.020
Echocardiographic data
 LVEF (%) 65.3 ± 6.3 63.9 ± 6.3 65.7 ± 6.3 0.052
 LVDdi (mm/m2) 25.7 ± 4.2 26.7 ± 4.0 25.4 ± 4.2 0.025
 LVSdi (mm/m2) 16.4 ± 3.0 17.3 ± 3.2 16.3 ± 5.0 0.137
 LAV index (ml/m2) 49.0 ± 15.6 58.4 ± 17 46.5 ± 14.2 <  0.001
 TAPSE (mm) 19.5 ± 3.1 18.7 ± 2.7 19.7 ± 3.1 0.016
 S’TV (cm/s) 11.4 ± 2.2 11.3 ± 2.5 12.1 ± 6.9 0.431
 RAP (mmHg) 7.6 ± 3.4 9.2 ± 4.2 7.2 ± 3.0 <  0.001
 Mean PAP (mmHg) 23.7 ± 7.2 26.8 ± 8.2 22.7 ± 6.5 0.002
 PASP (mmHg) 38.3 ± 11.5 45.0 ± 14.7 36.3 ± 9.5 <  0.001
Outcomes
 Death and heart failure 57 (19.0) 29 (44.6) 28 (11.9) <  0.001
 Heart failure visit 39 (13.0) 24 (36.9) 15 (6.4) <  0.001
 Heart failure hospitalization 20 (6.7) 9 (13.8) 11 (4.7) 0.020
 Death 26 (8.7) 8 (12.3) 18 (7.7) 0.240
  1. Data are expressed as number (percentage) and mean ± standard deviation
  2. Abbreviations: AF atrial fibrillation, FTR functional tricuspid regurgitation, LAV left atrial volume, LVDdi left ventricular diastolic dimension index, LVEF left ventricular ejection fraction, LVSdi left ventricular systolic dimension index, PAP pulmonary artery pressure, PASP pulmonary artery systolic pressure, RAP right atrial pressure, S’TV peak systolic myocardial velocity of lateral tricuspid annulus, TAPSE tricuspid annular plane systolic excursion