Table 1 Baseline characteristics, echocardiographic data and outcomes in all patients and the comparisons between patients with significant and insignificant functional tricuspid regurgitation
Variables | All patients (n = 300) | Significant FTR (n = 65) | Insignificant FTR (n = 235) | P-value |
|---|---|---|---|---|
Baseline characteristics | ||||
Age (years) | 68.8 ± 10.8 | 71.3 ± 10.3 | 68.1 ± 10.9 | 0.034 |
Female gender | 150 (50.0) | 45 (68.2) | 105 (44.7) | < 0.001 |
Non-paroxysmal AF | 196 (65.3) | 53 (81.5) | 143 (60.9) | 0.010 |
CHA2DS2-VASc score | 3.3 ± 1.7 | 3.6 ± 1.8 | 3.2 ± 1.7 | 0.103 |
Hypertension | 235 (78.3) | 50 (76.9) | 185 (79.1) | 0.710 |
Dyslipidemia | 153 (51.0) | 24 (36.9) | 129 (54.9) | 0.010 |
Diabetes mellitus | 105 (35.0) | 17 (26.2) | 88 (37.4) | 0.091 |
History of stroke | 88 (29.3) | 18 (28.1) | 70 (29.8) | 0.796 |
History of heart failure | 45 (15.0) | 11 (16.9) | 34 (14.5) | 0.624 |
Diuretics | 58 (19.3) | 20 (30.8) | 38 (16.2) | 0.020 |
Echocardiographic data | ||||
LVEF (%) | 65.3 ± 6.3 | 63.9 ± 6.3 | 65.7 ± 6.3 | 0.052 |
LVDdi (mm/m2) | 25.7 ± 4.2 | 26.7 ± 4.0 | 25.4 ± 4.2 | 0.025 |
LVSdi (mm/m2) | 16.4 ± 3.0 | 17.3 ± 3.2 | 16.3 ± 5.0 | 0.137 |
LAV index (ml/m2) | 49.0 ± 15.6 | 58.4 ± 17 | 46.5 ± 14.2 | < 0.001 |
TAPSE (mm) | 19.5 ± 3.1 | 18.7 ± 2.7 | 19.7 ± 3.1 | 0.016 |
S’TV (cm/s) | 11.4 ± 2.2 | 11.3 ± 2.5 | 12.1 ± 6.9 | 0.431 |
RAP (mmHg) | 7.6 ± 3.4 | 9.2 ± 4.2 | 7.2 ± 3.0 | < 0.001 |
Mean PAP (mmHg) | 23.7 ± 7.2 | 26.8 ± 8.2 | 22.7 ± 6.5 | 0.002 |
PASP (mmHg) | 38.3 ± 11.5 | 45.0 ± 14.7 | 36.3 ± 9.5 | < 0.001 |
Outcomes | ||||
Death and heart failure | 57 (19.0) | 29 (44.6) | 28 (11.9) | < 0.001 |
Heart failure visit | 39 (13.0) | 24 (36.9) | 15 (6.4) | < 0.001 |
Heart failure hospitalization | 20 (6.7) | 9 (13.8) | 11 (4.7) | 0.020 |
Death | 26 (8.7) | 8 (12.3) | 18 (7.7) | 0.240 |