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Table 4 A hierarchical regression of serum UA predicting cognitive function in female CHF patients (n = 71)

From: The relationship between serum uric acid and cognitive function in patients with chronic heart failure

 

Cognitive function

β

95% CI

R2

ΔR2

P-value

 

Lower

Upper

   

Block 1

–

–

–

0.672

–

0.000**

Age

−0.479

−0.677

− 0.282

  

0.000**

Educational level

0.334

0.173

0.495

  

0.000**

NYHA function class

−0.026

−0.209

0.157

  

0.774

LVEF

0.140

−0.041

0.320

  

0.128

BMI

0.073

−0.111

0.257

  

0.430

Hemoglobin

0.005

−0.184

0.193

  

0.961

hs-CRP

−0.234

−0.415

− 0.053

  

0.012*

eGFR

−0.128

−0.317

0.062

  

0.183

Hypertension

−0.115

−0.291

0.061

  

0.195

Type 2 diabetes mellitus

0.008

−0.164

0.180

  

0.925

Atrial fibrillation

0.033

−0.142

0.208

  

0.704

SDS score

−0.260

−0.451

− 0.070

  

0.008**

Block 2

–

–

–

0.672

0.000

0.955

Serum UA

−0.005

−0.185

0.175

  

0.955

  1. UA uric acid, CHF chronic heart failure, NYHA New York Heart Association, LVEF left ventricular fraction, BMI body mass index, hs-CRP hypersensitive C-reactive protein, eGFR estimated glomerular filtration rate, SDS self-rating depression scale
  2. β standardized coefficients, CI confidence interval
  3. * P < 0.05; ** P < 0.01