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Table 1 Characteristics of patients with discrepancies between HbA1c and FPG

From: Admission fasting plasma glucose is associated with in-hospital outcomes in patients with acute coronary syndrome and diabetes: findings from the improving Care for Cardiovascular Disease in China - Acute Coronary Syndrome (CCC-ACS) project

 

HbA1c ≥ 6.5% and FPG < 7.0 mmol/L

(n = 1761)

HbA1c < 6.5% and FPG ≥ 7.0 mmol/L

(n = 511)

P value

Age (years, mean [SD])

65.4(11.2)

65.4(10.9)

0.947

Male (n [%])

1184(67.2)

348(68.1)

0.713

Systolic blood pressure (mmHg, mean [SD])

135.0(22.8)

135.0(25.2)

0.895

Diastolic blood pressure (mmHg, median [IQR])

78.0(70.0, 87.0)

78.0(70.0, 89.0)

0.442

Heart rate (bpm. Median [IQR])

78.0(68.0, 87.0)

80.0(70.0, 90.0)

<  0.001

Current smoker (n [%])

508(28.8)

153(29.9)

0.047

Family history of CHD (n [%])

71(4.0)

21(4.1)

0.937

Hypertension (n [%])

1300(73.8)

403(78.9)

0.021

Previous acute myocardial infarction (n [%])

214(12.2)

58(11.4)

0.623

Previous coronary artery bypass grafting (n [%])

16(0.9)

4(0.8)

0.789

Atrial fibrillation history (n [%])

53(3.0)

14(2.7)

0.751

Heart failure history (n [%])

58(3.3)

19(3.7)

0.640

Cerebrovascular disease history (n [%])

185(10.5)

57(11.2)

0.675

Peripheral artery disease history (n [%])

31(1.8)

10(2.0)

0.769

Killip class (n [%])

  

0.289

 I or II

1505(85.5)

427(83.6)

 

 III or IV

256(14.5)

84(16.4)

 

Types of ACS (n [%])

  

<  0.001

 STEMI

716(40.7)

276(54.0)

 

 NSTE-ACS

1045(59.3)

235(46.0)

 

HbA1c (%, mean [SD])

8.2(14.7)

5.8(0.8)

<  0.001

FPG (mmol/L, mean [SD])/(mg/dl, mean [SD])

5.6(1.2)/100.8(21.6)

9.5(2.6)/171.0(46.8)

<  0.001

eGFR (ml min−1 [1.73 m]−2, mean [SD])

79.1(25.1)

76.4(27.3)

0.046

Hemoglobin (g/l, mean [SD])

132.1(20.4)

132.4(23.6)

0.192

Total cholesterol (mmol/L, median [IQR])/(mg/dl, median [IQR])

4.3(3.5, 5.1)/166.2(135.3, 197.2)

4.3(3.5, 5.1)/166.2(135.3, 197.2)

0.721

HDL-cholesterol (mmol/L, median [IQR])/(mg/dl, median [IQR])

1.0(0.8, 1.2)/38.7(30.9, 46.4)

1.0(0.8, 1.2)/38.7(30.9, 46.4)

0.931

LDL-cholesterol (mmol/L, median [IQR])/(mg/dl, median [IQR])

2.6(2.0, 3.2)/100.5(77.3, 123.7)

2.5(2.0, 3.2)/96.7(77.3, 123.7)

0.326

Triglyceride (mmol/L, median [IQR])/(mg/dl, median [IQR])

1.6(1.1, 2.4)/141.8(97.5, 212.6)

1.5(1.0, 2.3)/132.9(88.6, 203.8)

0.027

Oral glucose-lowering agents or insulin use before admission (n [%])

809(45.9)

288(56.4)

<  0.001

Therapy during hospitalization (n [%])

 Percutaneous coronary intervention

1170(66.4)

337(65.9)

0.836

 Aspirin

1644(93.4)

482(94.3)

0.432

 P2Y12 inhibitors

1603(91.0)

473(92.6)

0.276

 Statins

1653(93.9)

477(93.3)

0.669

 β-blockers

1146(65.1)

291(56.9)

0.001

 ACE inhibitor/angiotensin receptor blocker

917(52.1)

248(48.5)

0.159

Patients with referral (n [%])

587(33.3)

172(33.7)

0.891

  1. ACE Angiotensin-converting enzyme, ACS Acute coronary syndrome, CHD Coronary heart disease, eGFR Estimated glomerular filtration rate, FPG Fasting plasma glucose, HbA1c Glycosylated hemoglobin, HDL High-density lipoprotein, IQR Interquartile range, LDL Low-density lipoprotein, NSTE-ACS Non-ST-segment elevation acute coronary syndrome, SD Standard deviation, STEMI ST-segment elevation myocardial infarction