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Table 2 Univariate logistic regression analysis between early systolic blood pressure drop and worsening renal function

From: Early drop in systolic blood pressure, heart rate at admission, and their effects on worsening renal function in elderly patients with acute heart failure

Baseline characteristics

Odds ratio

95% CI

p-value

Age, yrs

0.98

0.92–1.04

0.5

Male, yes = 1, no = 0

0.69

0.34–1.42

0.3

Body weight at assessment, kg

0.99

0.96–1.02

0.4

Clinical scenario 1, yes = 1, no = 0

1.42

0.64–3.18

0.4

Clinical scenario 2, yes = 1, no = 0

1 (Ref.)

Clinical scenario 3, yes = 1, no = 0

1.04

0.27–3.99

0.96

Clinical scenario 4, yes = 1, no = 0

1.33

0.43–4.08

0.6

Ejection fraction, %

0.18

0.96–1.01

0.2

Current smoking, yes = 1, no = 0

1.16

0.53–2.57

0.7

Daily alcohol intake, yes = 1, no = 0

0.14

0.15–1.32

0.1

Hypertension, yes = 1, no = 0

3.48

1.02–11.8

0.046

Diabetes mellitus, yes = 1, no = 0

0.97

0.46–2.06

0.9

Lipid disorder, yes = 1, no = 0

1.23

0.62–2.58

0.5

Chronic atrial fibrillation, yes = 1, no = 0

0.91

0.39–2.12

0.8

Baseline laboratory values:

 Log BNP

1.36

0.97–1.91

0.08

 Hemoglobin, g/dL

0.97

0.82–1.15

0.7

 BUN, mg/dL

0.997

0.98–1.02

0.8

 Serum creatinine, g/dL

1.12

0.83–1.53

0.5

Medication at baseline:

 ACEI use, yes = 1, no = 0

0.29

0.04–2.20

0.2

 ARB use, yes = 1, no = 0

1.42

0.70–2.89

0.3

 CCB use, yes = 1, no = 0

0.83

0.40–1.72

0.6

 Beta-blocker, yes = 1, no = 0

1.47

0.70–3.01

0.3

 Loop diuretics, yes = 1, no = 0

1.48

0.73–3.04

0.3

Medication during admission

 I.V. loop diuretic use, yes = 1, no = 0

2.93

0.99–8.65

0.052

 I.V. isosorbide dinitrate, yes = 1, no = 0

3.18

1.54–6.58

0.002

 I.V. carperitide use, yes = 1, no = 0

0.66

0.15–3.01

0.6

Blood pressure and heart rate parameters

 Systolic blood pressure at admission, mmHg

1.02

1.01–1.03

0.001

 Diastolic blood pressure at admission, mmHg

1.01

0.99–1.03

0.5

 Heart rate at admission, mmHg

0.987

0.97–0.999

0.046

 Early systolic blood pressure drop, mmHg

1.02

1.01–1.03

0.001

  1. Each parameters was included to the simple logistic regression model for worsening renal function. Patients with clinical scenario 2 were the reference (Ref.) group. BNP indicates B-type natriuretic peptide; BUN, blood urea nitrogen; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II receptor blocker; CCB, calcium channel blocker; I.V., intravenous