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Table 1 Baseline characteristics of 49 patients with HCM

From: Quantitative fragmented QRS has a good diagnostic value on myocardial fibrosis in hypertrophic obstructive cardiomyopathy based on clinical-pathological study

 

All patients

Patients with HOCM

 

P value

(n = 69)

With fQRS

Without fQRS

 

(n = 38)

(n = 31)

Age,years

46.1 ± 14.4

43.7 ± 15.6

49 ± 12.3

0.129

Male,%

43 (62.3)

22 (57.9)

21 (67.7)

0.401

Dyspnea,%

61 (88.4)

34 (89.5)

27 (87.1)

1

NYHA III/IV,%

22 (31.9)

13 (34.2)

9 (29)

0.646

History of syncope,%

19 (27.5)

13 (34.2)

6 (19.4)

0.169

History of hypertension,%

15 (21.7)

6 (15.8)

9 (29)

0.185

History of diabetes mellitus,%

6 (8.7)

4 (10.5)

2 (6.5)

0.867

Family history of HCM or SCD,%

5 (7.2)

2 (5.3)

3 (9.7)

0.813

NSVT,%

12 (17.4)

7 (18.4)

5 (16.1)

0.803

AF,%

9 (13)

5 (13.2)

4 (12.9)

1

Bundle branch block,%

4 (5.8)

2 (5.3)

2 (6.5)

1

ICD,%

0 (0)

0 (0)

0 (0)

1

SAM,%

68 (98.6)

38 (100)

30 (96.8)

0.449

Mitral regurgitation

2 (1–2)

2 (1–3)

2 (1–2)

0.373

Calcium antagonist,%

25 (36.2)

11 (28.9)

14 (45.2)

0.163

Beta blocker,%

51 (73.9)

33 (86.8)

18 (58.1)

0.007

ACEI/ARB,%

2 (2.9)

0 (0)

2 (6.5)

0.204

Diuretics,%

24 (34.8)

11 (28.9)

13 (41.9)

0.26

CMR

 Septal wall thickness,mm

25 (21–29)

26 (21.8–29)

24 (19–29)

0.637

 Left atrium diameter,mm

41.8 ± 7.9

42 ± 8.4

41.5 ± 7.3

0.802

 LV end-diastolic diameter,mm

45.6 ± 4.2

46.1 ± 4

44.9 ± 4.3

0.236

 LVMI,g/m2

88.9 (73.3–117.4)

91.5 (77.2–133.5)

83 (66.9–110)

0.385

 LVEF,%

64.8 ± 9.6

64.1 ± 9.6

65.8 ± 9.8

0.47

 LVEDVI,ml/m2

83.7 ± 20.4

87.7 ± 23.2

78.7 ± 15.4

0.069

 LVESVI,ml/m2

28.7 (21.8–36.3)

31.7 (23.7–39.4)

25.9 (19.9–30.9)

0.054

 LGE at 2SD,%

27.5 (22.4–38.2)

28 (22.5–39.9)

26.9 (19–37.2)

0.403

 LGE at 4SD,%

12.8 (6.9–19.1)

14.4 (9.5–21.9)

11.9 (5.8–16.7)

0.067

 LGE at 6SD,%

6.2 (1.9–8.7)

6.7 (3.9–10.8)

4.2 (1.6–7.5)

0.04

 LGE at 8SD,%

2.4 (0.45–4.65)

3.2 (0.62–5.9)

1.9 (0.33–3.4)

0.057

BSA,m2

1.8 (1.6–1.9)

1.7 (1.6–1.9)

1.8 (1.7–1.9)

0.05

  1. Data are presented as the mean value SD (p values for 2-sided Student’s t test) or median and interquartile (p values for Mann-Whitney test) or percentage of patients (p values for chi-square test). Volumes are indexed to body surface area. ACEI angiotensin-converting enzyme inhibitor, AF atrial fibrillation, ARB angiotensin receptor blocker, BSA body surface area, ICD implantable cardioverter-defibrillator, HCM hypertrophic cardiomyopathy, LGE late gadolinium enhancement, LVEDVI Left ventricle end diastolic volume index, LVEF left ventricular ejection fraction, LVESVI Left ventricle end systolic volume index, LVMI left ventricle mass index, NYHA New York Heart Association, NSVT non-sustained ventricular tachycardia, SAM systolic anterior motion, SCD sudden cardiac death,SD standard deviation
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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