Table 1 Baseline characteristics
Parameters | Intracoronary prourokinase group (N = 25) | Control group (N = 25) | P value |
|---|---|---|---|
Age, mean ± SD, years | 59.48 ± 14.36 | 60.96 ± 12.56 | 0.700 |
Male, No. (%) | 21 (80.8) | 22 (88.0) | 0.440 |
BMI, mean ± SD, kg/m2 | 25.69 ± 2.94 | 25.45 ± 2.89 | 0.769 |
Current smoker, No. (%) | 12 (48.0) | 13 (52.0) | 0.777 |
Angina history, No. (%) | 13 (52.0) | 11 (44.0) | 0.571 |
Hypertension, No. (%) | 17 (47.2) | 19 (52.8) | 0.529 |
Diabetes mellitus, No. (%) | 8 (32.0) | 6 (24.0) | 0.528 |
Dyslipidemia, No. (%) | 8 (30.0) | 5 (20.0) | 0.333 |
Heart rate, mean ± SD, bpm | 73.24 ± 14.22 | 77.40 ± 16.32 | 0.341 |
SBP, mean ± SD, mmHg | 130.36 ± 24.31 | 131.72 ± 24.93 | 0.846 |
DBP, mean ± SD, mmHg | 77.76 ± 15.56 | 81.92 ± 18.13 | 0.388 |
Killip grade, No. (%) | Â | Â | 0.465 |
 I | 10 (40.0) | 14 (56.0) |  |
 II | 11 (44.0) | 9 (36.0) |  |
 III | 4 (16.0) | 2 (8.0) |  |
Creatinine, mean ± SD, μmoI/L | 85.32 ± 28.85 | 79.56 ± 16.23 | 0.389 |
GRF, mean ± SD, ml/min | 91.17 ± 26.26 | 96.62 ± 20.49 | 0.418 |
RBC, mean ± SD, 10^9/L | 4.54 ± 0.52 | 4.51 ± 0.55 | 0.845 |
NLR, mean ± SD | 8.20 ± 5.53 | 8.19 ± 6.94 | 0.996 |
PLT, mean ± SD, 10^9/L | 191.53 ± 91.73 | 220.92 ± 46.34 | 0.159 |
MPV, mean ± SD, fL | 7.70 ± 2.70 | 8.43 ± 1.89 | 0.222 |
Medications prior to PCI, No.(%) | |||
 Aspirin | 25 (100.0) | 25 (100.0) | 1.000 |
 Ticagrelor | 25 (100.0) | 25 (100.0) | 1.000 |
 Statins | 25 (100.0) | 25 (100.0) | 1.000 |
 Heparin | 25 (100.0) | 25 (100.0) | 1.000 |
 IIb/IIIa inhibitor | 18 (72.0) | 14 (56.0) | 0.239 |
 Intravenous nitroglycerin | 15 (60.0) | 18 (72.0) | 0.370 |
Medications at discharge, No.(%) | |||
 ACEI | 16 (64.0) | 20 (80.0) | 0.208 |
 B-blocker | 14 (56.0) | 18 (72.0) | 0.239 |
 Statins | 25 (100.0) | 25 (100.0) | 1.000 |
 DAPT | 25 (100.0) | 25 (100.0) | 1.000 |