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Table 4 COX proportional hazard model for the cardiac death of the study cohort

From: Comparison of the prognosis for different onset stage of cardiogenic shock secondary to ST-segment elevation myocardial infarction

 

Univariate

Multivariate

HR

95% CI

p-value

HR

95% CI

p-value

Age

1.066

1.041–1.091

< 0.001

1.068

1.038–1.099

< 0.001

Male sex

3.543

2.132–5.889

< 0.001

2.100

1.196–3.688

0.01

Hypertension

1.968

1.082–3.582

0.027

–

–

–

Diabetes

1.429

0.835–2.444

0.193

–

–

–

Smoking

0.684

0.288–1.011

0.099

–

–

–

Prior Stroke

1.865

1.007–3.453

0.047

1.989

1.124–3.523

0.018

Hyperlipdemia

0.177

0.024–1.276

0.086

–

–

–

Known kidney dysfunction

1.764

1.035–3.007

0.037

–

–

–

Prior MI

1.345

0.328–5.519

0.681

–

–

–

Pre-procedural SBP

0.992

0.975–1.001

0.081

–

–

–

Pre-procedural HR

1.019

1.003–1.035

0.017

–

–

–

LVEF, per % increased

0.949

0.909–0.991

0.017

0.911

0.871–0.954

< 0.001

TG, per mmol/L increased

0.889

0.679–1.165

0.394

–

–

–

TCh, per mmol/L increased

0.811

0.623–1.055

0.118

–

–

–

LDL-C, per mmol/L increased

0.74

0.518–1.057

0.098

   

HDL-C, per mmol/L increased

1.075

0.572–2.020

0.823

–

–

–

Multivessel lesions

1.954

1.191–3.208

0.008

–

–

–

Time of symptom-wire, per hour increased

1.011

0.999–1.023

0.081

–

–

–

IABP utility

2.004

0.951–4.224

0.068

–

–

–

Shock index (per 0.1 increased)

1.2

1.079–1.334

0.001

–

–

–

Anterior MI

0.795

0.479–1.319

0.374

–

–

–

Onset stage of CS

 Non- CS (reference)

1

–

–

1

–

–

 CS on admission

3.345

1.496–7.479

0.003

2.739

1.210–6.204

0.016

 developed CS

2.346

1.252–4.395

0.008

2.233

1.164–4.286

0.016

Killips Classification

 Killips = 1(reference)

1

–

–

–

–

–

 Killips = 2

2.737

1.502–4.988

0.001

–

–

–

 Killips = 3

3.84

1.694–8.700

0.007

–

–

–

 Killips = 4

4.13

1.460–11.681

0.001

–

–

–

post-PCI TIMI flow of IRA

 3(reference)

1

–

–

–

–

–

 2

4.403

1.071–18.098

0.04

–

–

–

 1

6.488

1.191–27.228

0.035

–

–

–

  1. MACE Major adverse cardiac events, CS Cardiogenic shock, SBP Stytolic blood pressure, HR Heart rate, bpm beats per minute, LVEF Left ventricular ejection fraction, TG Triglyceride, LDL-C Low density lipoprotein cholesterol, HDL-C High density lipoprotein cholesterol, TC Total cholesterol, IABP Intra-aortic balloon pump, MI Myocardial infarction, TIMI Thrombolysis in myocardial infarction, IRA Infarct-related artery, PCI Percutaneous coronary intervention