Table 1 Demographic characteristics and baseline clinical information
Variables | All (n = 221) | Female (n = 125) | Male (n = 96) | P |
|---|---|---|---|---|
Age (year)* | 81.4 (8.4) | 81.2 (8.0) | 81.7 (8.9) | 0.626 |
Body height (cm)* | 156.9 (9.5) | 150.5 (6.5) | 165.2 (5.7) | <  0.001 |
Body weight (kg)* | 60.2 (12.8) | 55.7 (11.2) | 66.2 (12.3) | <  0.001 |
BMI (kg/m2)* | 24.4 (4.2) | 24.5 (4.4) | 24.2 (3.9) | 0.556 |
BMI ≥ 20 kg/m2 | 189 (85.5) | 108 (86.4) | 81 (84.4) | 0.672 |
Normal weight (BMI < 25 kg/m2) | 126 (57.0) | 68 (54.4) | 58 (60.4) | 0.614 |
Overweight (25 kg/m2 ≤ BMI < 30 kg/m2) | 78 (35.3) | 46 (36.8) | 32 (33.3) |  |
Obesity (BMI ≥ 30 kg/m2) | 17 (7.7) | 11 (8.8) | 6 (6.3) |  |
New BMI (kg/m2)* | 25.4 (4.5) | 26.0 (4.8) | 24.5 (3.9) | 0.011 |
New BMI ≥ 20 kg/m2 | 192 (86.9) | 111 (88.8) | 81 (84.4) | 0.422 |
Normal weight (New BMI < 25 kg/m2) | 106 (48.0) | 53 (55.2) | 53 (42.4) | 0.015 |
Overweight (25 kg/m2 ≤ New BMI < 30 kg/m2) | 92 (41.6) | 53 (42.4) | 39 (40.6) |  |
Obesity (New BMI ≥ 30 kg/m2) | 23 (10.4) | 19 (15.2) | 4 (4.2) |  |
Body surface area (m2)* | 1.6 (0.2) | 1.5 (0.2) | 1.7 (0.2) | <  0.001 |
Lean body mass (kg)* | 44.4 (8.4) | 38.7 (4.5) | 51.7 (6.3) | <  0.001 |
Lean body mass index (kg/m2)* | 17.9 (1.8) | 17.1 (1.4) | 18.9 (1.8) | <  0.001 |
Logistic EuroSCORE (%)* | 18 (15.0) | 18.5 (16.1) | 17.3 (13.5) | 0.554 |
Hypertension | 161 (72.9) | 89 (71.2) | 72 (75.0) | 0.529 |
Diabetes | 83 (37.6) | 43 (34.4) | 40 (41.7) | 0.269 |
Hyperlipidemia | 99 (44.8) | 52 (41.6) | 47 (49.0) | 0.276 |
NYHA class III-IV | 144 (65.2) | 81 (64.8) | 63 (65.6) | 0.898 |
Coronary artery disease | 93 (42.1) | 39 (31.2) | 54 (56.3) | < 0.001 |
Prior myocardial infarction | 14 (6.3) | 8 (6.4) | 6 (6.3) | 0.964 |
Prior CABG | 10 (4.5) | 6 (4.8) | 4 (4.2) | 0.822 |
Prior PCI | 75 (33.9) | 28 (22.4) | 47 (49.0) | < 0.001 |
Peripheral vascular disease | 59 (26.7) | 25 (20.0) | 34 (35.4) | 0.010 |
Cerebrovascular accident | 51 (23.2) | 24 (19.2) | 27 (28.4) | 0.108 |
Pulmonary disease | 48 (21.7) | 23 (18.4) | 25 (26.0) | 0.172 |
Pre-existing pacemaker | 5 (2.3) | 2 (1.6) | 3 (3.1) | 0.655 |
Atrial fibrillation | 47 (21.3) | 29 (23.2) | 18 (18.8) | 0.423 |
Bicuspid aortic valve | 26 (11.8) | 14 (11.2) | 12 (12.5) | 0.766 |
Serum creatinine (mg/dl)* | 1.8 (2.1) | 1.6 (1.9) | 2 (2.3) | 0.145 |
eGFR (ml/min)* | 40.8 (22.1) | 38.7 (20.4) | 43.6 (23.9) | 0.101 |
eGFR < 60 ml/min | 182 (82.4) | 105 (84.0) | 77 (80.2) | 0.464 |
Dialysis | 17 (7.7) | 8 (6.4) | 9 (9.4) | 0.411 |
Echocardiographic findings | ||||
 LV ejection fraction (%)* | 55.2 (10.2) | 56.5 (9.4) | 53.4 (10.9) | 0.026 |
 Aortic valve area (cm2)* | 0.7 (0.2) | 0.6 (0.2) | 0.7 (0.2) | < 0.001 |
 Mean pressure gradient (mmHg)* | 44 (18.5) | 45.1 (19.6) | 42.5 (16.9) | 0.292 |
 Peak pressure gradient (mmHg)* | 71.6 (29.3) | 73.3 (30.6) | 69.5 (27.5) | 0.336 |
 PA pressure > 60 mmHg | 187 (86.6) | 101 (82.1) | 86 (92.5) | 0.027 |
 MR, moderate or severe | 40 (18.1) | 29 (23.2) | 11 (11.5) | 0.025 |
 AR, moderate or severe | 35 (15.8) | 19 (15.2) | 16 (16.7) | 0.767 |
 LV mass (g)* | 224.7 (72.2) | 207.2 (65.5) | 246.3 (74.7) | < 0.001 |