Fig. 2
From: Laparoscopic based renal denervation in a canine neurogenic hypertension model
a and b: Changes in blood pressure (SBP, DBP, ISBP and IDBP) at pre- and post-induction of hypertension and post- procedure of hypertension. SBP = systolic blood pressure. DBP = diastolic blood pressure. ISBP = invasive systolic blood pressure. IDBP = invasive diastolic blood pressure. **P < 0.01, ****P < 0.0001.Histological Examination of the Target Nerve Bundles (c) 8 weeks after Neurogenic hypertension modeling in sham group (H&E × 100, × 400). Photomicrograph of a histologic cross-section of complete renal sympathetic nerve tissue was shown before RDN. (d) 8 weeks after ablation in RDN group (H&E × 100, × 400). The renal artery with intact wall and endothelium was surrounded by the damaged nerve fibers. The nerve fibers show coagulation necrosis and absence of nuclei. Fluorescent immunostaining shows the renal artery with intact wall and endothelium in RDN group at 8 weeks after ablation procedure. (E × 50, F × 100, G × 200, H × 400)