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Fig. 4 | BMC Cardiovascular Disorders

Fig. 4

From: Protective effects of rolipram on endotoxic cardiac dysfunction via inhibition of the inflammatory response in cardiac fibroblasts

Fig. 4

Effects of rolipram on inflammatory cell infiltration and cardiac function of the hearts of endotoxic mice. Inflammatory cell infiltration and heart function were examined on the endotoxic mice model by pathological analysis, flow cytometry and echocardiography, respectively. a. Representative pictures of HE staining of heart tissue from endotoxic mice (200×, the arrows showed the inflammatory cells). b. The inflammatory scores of the histopathological sections. c. The Cd45 positive cell rate in the single cells harvested from the heart tissue. d. The Ly6g positive cell rate in the Cd45 positive cells harvested from the heart tissue. e. Representative pictures of M-mode at the level of left ventricular short axis view. f. Analysis of left ventricular ejection fraction (EF) of the hearts of endotoxic mice. a, control + DMSO, b, control + rolipram, c, LPS + DMSO, d, LPS + rolipram. * represents P < 0.05, n = 5

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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