Fig. 1

Effects of LPS on the cardiac fibroblast inflammatory responses and DUSP1 expression. After cardiac fibroblasts were stimulated with 1 μg/ml LPS for 6 h, the mRNA levels and supernatant concentrations of inflammatory mediators were measured by qRT-PCR and ELISA, respectively. a-c and g, Relative fold change to control group of TNF-ɑ, IL-6, IL-1β and DUSP1 mRNA expression. d-f, Concentrations of TNF-ɑ, IL-6 and IL-1β in the supernatant. h, DUSP1 protein expression in cardiac fibroblasts (original, uncropped blot was shown in supplement Fig. S1A). I, Protein quantification of DUSP1. * represents P < 0.05 compared with the control group