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Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: Identification of transcription factors MYC and C/EBPβ mediated regulatory networks in heart failure based on gene expression omnibus datasets

Fig. 3

Metabolism and insulin signaling pathway are suppressed in failing heart patients. a Functional pathways enrichment analysis of the common differentially expressed 90 genes in failing heart tissues. b Differentially expressed genes from cysteine, methionine, pyrimidine and purine metabolism signaling pathway were represented using heatmaps. c Enrichment plots showed the enriched insulin signaling pathway in GSE5406, GSE16499 and GSE68316 datasets. Enrichment of NES and P values were shown. d Box plots showed the expression levels of MAP2K1 in GSE5406, GSE16499 and GSE68316 datasets. P values showed the difference of MAP2K1 expression levels between failing heart tissues and normal heart tissues determined by Student’s t test

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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