Comparison of predictive value of NT-proBNP, sST2 and MMPs in heart failure patients with different ejection fractions

Table 3 Spearman correlation analysis of plasma sST2 levels and related factors in patients with HF

Projects	HFpEF group (n = 60)		HFmrEF group (n = 28)		HFrEF group (n = 25)
–	r	P	r	P	r	P
Age (Years old)	+ 0.058	0.685	−0.087	0.660	+ 0.106	0.614
Male [Case (%)]	+ 0.185	0.276	+ 0.240	0.219	−0.046	0.670
BMI (kg/m²)	+ 0.028	0.833	−0.087	0.660	−0.055	0.792
Diabetes Mellitus [Case (%)]	+ 0.191	0.075	−0.118	0.462	+ 0.059	0.727
Atrial fibrillation [Case (%)]	+ 0.087	0.415	+ 0.100	0.553	+ 0.277	0.103
Coronary heart disease [Case (%)]	+ 0.102	0.341	−0.136	0.394	+ 0.062	0.717
Hypertension [Case (%)]	+ 0.120	0.263	−0.132	0.441	+ 0.289	0.089
Systolic blood pressure (mmHg)	−0.005	0.969	+ 0.048	0.808	+ 0.037	0.861
Diastolic blood pressure (mmHg)	−0.014	0.913	+ 0.355	0.063	+ 0.105	0.618
Triglyceride (mmol/L)	+ 0.05	0.705	−0.101	0.609	−0.072	0.733
Total cholesterol (mmol/L)	−0.132	0.314	+ 0.252	0.196	−0.251	0.226
LDL-C (mmol/L)	−0.090	0.496	+ 0.360	0.060	−0.231	0.132
eGFR [ml/(min·1.73m²)]	−0.117	0.726	+ 0.008	0.969	−0.195	0.351
MMP-2 (ng/ml)	+ 0.330	0.010	+ 0.505	<0.05	+ 0.562	0.003
MMP-9 (ng/ml)	+ 0.558	<0.05	+ 0.376	0.001	+ 0.811	<0.05
NT-proBNP (pg/ml)	+ 0.493	<0.05	+ 0.448	<0.05	+ 0.688	<0.05

Note: BMI: body mass index, LDL-C: low density lipoprotein cholesterol, eGFR: estimated glomerular filtration rate

ISSN: 1471-2261