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Table 2 Laboratory data and incidence of CI-AKI (n (%) or median [IQR]) (n = 284)

From: Effect of continuous use of metformin on kidney function in diabetes patients with acute myocardial infarction undergoing primary percutaneous coronary intervention

 

metformin

n = 119

No Metformin

n = 165

p value

HbA1c(%)

7.0 [3.6–14.2]

7.8 [6.9–8.8]

0.194

Hb(g/l)

141 [126–152]

120 [110–140]

0.079

cTnI peak (ng/ml)

7.0 [3.6–14.2]

7.8 [6.9–8.8]

0.842

Creatinine

 Baseline (μmol/l)

76 [66–86]

73 [61–84]

0.105

 Post PCI (μmol/l)

83 [72–98]

76 [64–76]

0.012

 Relative creatinine change

11% [6–20%]

11% [5–22%]

0.858

post PCI (%)

  ≥ 50% increase

5 (4.2%)

9 (5.5%)

0.630

 Absolute creatinine change

7.9 [2.4–13.2]

6.7 [0.2–12.7]

0.198

post PCI (%) (μmol/l)

  ≥ 27 μmol/l(0.3 mg/dl)

15 (12.6%)

15 (9.1%)

0.342

eGFR (ml/min/1.73m2)

 Baseline (ml/min/1.73m2)

89 [73–104]

94 [72–113]

0.170

 eGFR≤60 ml/min/1.73m2

9 (7.6%)

21 (12.7%)

0.163

 Post PCI (ml/min/1.73m2)

77 [65–95]

87 [67–102]

0.092

 Relative eGFR change

13.4% [6.4–25.1%]

13.5% [5.2–24.3%]

0.449

post PCI (%)

 Absolute eGFR change

−7 [−16; 3]

−6 [−18; 3]

0.981

post PCI (ml/min/1.73m2)

 CI-AKI

15 (12.6%)

17 (10.3%)

0.545

  1. HbA1c glycosylated hemoglobin, Hb hemoglobin, eGFR glycosylated hemoglobin estimated glomerular filtration rate, cTnI cardiac troponin I, PCI percutaneous coronary intervention, CI-AKI contrast induced-acute renal injury