From: Brazilian cardio-oncology: the 10-year experience of the Instituto do Cancer do Estado de Sao Paulo
Variable | Cardiotoxicity | General | Perioperative | p |
---|---|---|---|---|
n = 448 | n = 2807 | n = 1270 | ||
Male, n (%) | 105 (23.4%) | 1242 (44.2%) | 592 (46.6%) | < 0.001ª |
Age (years), median and IQR | 59 (48–66) | 66 (58–74) | 69 (62–76) | < 0.001b |
Cancer Type | < 0.001ª | |||
Gastrointestinal | 39 (8.7%) | 679 (24.2%) | 321 (25.3%) | |
Breast Cancer | 237 (52.9%) | 510 (18.2%) | 109 (8.6%) | |
Hematological | 118 (26.3%) | 574 (20.4%) | 21 (1.7%) | |
Head and neck | 5 (1.1%) | 183 (6.5%) | 143 (11.3%) | |
Skin, bone and soft tissue | 12 (2.7%) | 110 (3.9%) | 156 (12.3%) | |
Brain | 0 (0%) | 15 (0.5%) | 6 (0.5%) | |
Lung | 6 (1.3%) | 148 (5.3%) | 44 (3.5%) | |
Gynecological and urinary tract | 20 (4.5%) | 505 (18%) | 422 (33.2%) | |
Other / without specification | 11 (2.5%) | 83 (3%) | 48 (3.8%) | |
Diabetes | 67 (15%) | 635 (22.6%) | 379 (29.8%) | < 0.001ª |
Hypertension | 196 (43.8%) | 1649 (58.7%) | 890 (70.1%) | < 0.001ª |
Dyslipidemia | 87 (19.7%) | 687 (25.7%) | 459 (36.2%) | < 0.001ª |
Current smoking | 29 (6.5%) | 214 (8%) | 126 (9.9%) | 0.086ª |
Previous smoker | 107 (24.2%) | 907 (33.9%) | 457 (36%) | < 0.001ª |
Obesity | 49 (11%) | 262 (9.8%) | 130 (10.3%) | 0.343ª |
Hyperuricemia | 9 (2%) | 33 (1.2%) | 28 (2.2%) | 0.091ª |
Carotid Disease | 2 (0.5%) | 20 (0.7%) | 15 (1.2%) | 0.414ª |
Peripheral arterial disease | 3 (0.7%) | 30 (1.1%) | 39 (3.1%) | < 0.001ª |
Cerebrovascular Disease | 11 (2.5%) | 171 (6.4%) | 94 (7.4%) | 0.003ª |
Atrial fibrillation / flutter | 15 (3.4%) | 270 (10.1%) | 100 (7.9%) | < 0.001ª |
Coronary artery disease | 22 (4.9%) | 358 (13.5%) | 236 (18.6%) | < 0.001ª |
LVEDD (mm), median and IQR | 49 (45–53) | 47 (43–51) | 49 (44–53) | < 0.001b |
LVESD (mm), median and IQR | 35 (31–43) | 32 (29–38) | 32 (29–38) | < 0.001b |
LVEF (%), median and IQR | 55 (41–63) | 62 (55–66) | 62 (55–66) | < 0.001b |