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Table 3 Comparison of clinical characteristics according to the type of outpatient care

From: Brazilian cardio-oncology: the 10-year experience of the Instituto do Cancer do Estado de Sao Paulo

Variable

Cardiotoxicity

General

Perioperative

p

n = 448

n = 2807

n = 1270

 

Male, n (%)

105 (23.4%)

1242 (44.2%)

592 (46.6%)

< 0.001ª

Age (years), median and IQR

59 (48–66)

66 (58–74)

69 (62–76)

< 0.001b

Cancer Type

   

< 0.001ª

 Gastrointestinal

39 (8.7%)

679 (24.2%)

321 (25.3%)

 

 Breast Cancer

237 (52.9%)

510 (18.2%)

109 (8.6%)

 

 Hematological

118 (26.3%)

574 (20.4%)

21 (1.7%)

 

 Head and neck

5 (1.1%)

183 (6.5%)

143 (11.3%)

 

 Skin, bone and soft tissue

12 (2.7%)

110 (3.9%)

156 (12.3%)

 

 Brain

0 (0%)

15 (0.5%)

6 (0.5%)

 

 Lung

6 (1.3%)

148 (5.3%)

44 (3.5%)

 

 Gynecological and urinary tract

20 (4.5%)

505 (18%)

422 (33.2%)

 

 Other / without specification

11 (2.5%)

83 (3%)

48 (3.8%)

 

Diabetes

67 (15%)

635 (22.6%)

379 (29.8%)

< 0.001ª

Hypertension

196 (43.8%)

1649 (58.7%)

890 (70.1%)

< 0.001ª

Dyslipidemia

87 (19.7%)

687 (25.7%)

459 (36.2%)

< 0.001ª

Current smoking

29 (6.5%)

214 (8%)

126 (9.9%)

0.086ª

Previous smoker

107 (24.2%)

907 (33.9%)

457 (36%)

< 0.001ª

Obesity

49 (11%)

262 (9.8%)

130 (10.3%)

0.343ª

Hyperuricemia

9 (2%)

33 (1.2%)

28 (2.2%)

0.091ª

Carotid Disease

2 (0.5%)

20 (0.7%)

15 (1.2%)

0.414ª

Peripheral arterial disease

3 (0.7%)

30 (1.1%)

39 (3.1%)

< 0.001ª

Cerebrovascular Disease

11 (2.5%)

171 (6.4%)

94 (7.4%)

0.003ª

Atrial fibrillation / flutter

15 (3.4%)

270 (10.1%)

100 (7.9%)

< 0.001ª

Coronary artery disease

22 (4.9%)

358 (13.5%)

236 (18.6%)

< 0.001ª

LVEDD (mm), median and IQR

49 (45–53)

47 (43–51)

49 (44–53)

< 0.001b

LVESD (mm), median and IQR

35 (31–43)

32 (29–38)

32 (29–38)

< 0.001b

LVEF (%), median and IQR

55 (41–63)

62 (55–66)

62 (55–66)

< 0.001b

  1. a: Chi-squared test, b: Kruskal-Wallis test
  2. LVEDD Left ventricular end-diastolic diameter, LVESD Left ventricular end systolic diameter, LVEF Left ventricular ejection fraction, ITQR Interquartile range