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Table 1 General characteristics of study subjects

From: Circulating heat shock protein 27 as a novel marker of subclinical atherosclerosis in type 2 diabetes: a cross-sectional community-based study

CharacteristicTotalIMT (−)IMT (+)P value
Subjects18611076
Age (years)67 (57–73)64 (53.75–71)70 (64.25–75)0.000*
Sex (male/female)74/11239/7135/410.147
Smoking (%)76.8878.1875.000.613
Alcohol (%)8.609.097.890.078
lipid-lowering drugs (%)50.9860.9151.320.194
CVD (%)20.4317.2725.000.199
Onset age of diabetes (years)57.12 ± 11.1654.76 ± 11.2960.47 ± 10.130.001*
Duration of diabetes (years)6 (3–10)6 (3–10)7 (4–12)0.370
BMI (kg/m2)24.63 ± 3.2124.46 ± 3.1924.88 ± 3.230.392
WC (cm)81.43 ± 8.7681.10 ± 8.7581.90 ± 8.810.544
WHR0.87 ± 0.060.87 ± 0.070.88 ± 0.060.077
SBP (mmHg)140 (130–150)140 (129.5–150)142 (135–160)0.001*
DBP (mmHg)84 (78–92)82 (76–90)86 (80–94.75)0.026*
FBG (mmol/L)7.80 (6.45–10.00)7.55 (6.3–9.65)8.60 (6.90–10.10)0.236
PBG (mmol/L)15.73 ± 6.0815.60 ± 6.1615.93 ± 6.000.717
Fasting insulin (pmol/L)12.20 (7.44–20.06)12.22 (7.35–18.81)12.20 (7.54–21.77)0.387
2 h insulin (pmol/L)46.49 (28.06–69.77)47.46 (29.43–70.23)43.99 (25.77–69.63)0.780
Fasting C peptide (ng/mL)2.94 (2.22–3.78)2.96 (2.23–3.72)2.91 (2.15–3.86)0.622
2 h C peptide (ng/mL)8.88 (6.61–11.74)8.84 (7.07–10.92)8.88 (6.45–12.67)0.191
HOMA-IR4.56 (2.39–7.99)4.11 (2.23–7.42)5.27 (2.72–9.22)0.359
HbA1c (%)6.70 (6.00–7.65)6.70 (6.00–7.65)6.80 (6.03–7.75)0.730
BUN (mmol/L)6.00 (5.00–7.15)5.85 (5.00–6.70)6.20 (5.20–7.70)0.224
Scr (μmol/L)65 (54–78)62 (52–76)68 (58–80)0.441
Serum uric acid (μmol/L)0.27 (0.24–0.33)0.28 (0.23–0.33)0.27 (0.24–0.33)0.887
eGFR (mL·min−1 1.73 m−2)121.15 ± 30.98124.15 ± 31.80116.74 ± 29.410.111
TC (mmol/L)5.26 ± 1.185.07 ± 0.995.54 ± 1.380.008*
TG (mmol/L)1.60 (1.07–2.16)1.50 (1.09–2.11)1.63 (1.01–2.28)0.482
LDL-C (mmol/L)3.00 (2.40–3.40)2.90 (2.40–3.30)3.00 (2.40–3.60)0.094
HDL-C (mmol/L)1.30 (1.05–1.50)1.20 (1.00–1.50)1.30 (1.10–1.60)0.266
UACR (μg/mg)14.42 (6.04–31.06)11.29 (4.59–24.94)20.17 (7.38–46.28)0.651
CRP (mg/L)3.05 (1.65–5.29)6.92 (4.23–9.60)8.80 (5.62–12.25)0.019*
IMT (mm)1.03 ± 0.420.78 ± 0.191.41 ± 0.380.000*
HSP27 (ng/mL)7.85 (4.78–10.92)6.93 (4.23–9.60)8.80 (5.62–12.25)0.007*
  1. P < 0.05 (*)