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Table 3 Univariable analysis of HRnV and HRnVm parameters

From: Heart rate n-variability (HRnV) and its application to risk stratification of chest pain patients in the emergency department

 

HRV

HR2V

HR3V

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

Mean NN

0.999 (0.998–1.000)

0.023*

0.999 (0.999–1.000)

0.023*

1.000 (0.999–1.000)

0.023*

SDNN

0.992 (0.986–0.999)

0.023*

0.996 (0.992–1.000)

0.028*

0.997 (0.995–1.000)

0.060

RMSSD

0.990 (0.982–0.998)

0.010*

0.992 (0.985–0.998)

0.011*

0.994 (0.988–0.999)

0.030*

Skewness

1.059 (0.991–1.132)

0.088

1.079 (0.981–1.186)

0.118

1.139 (1.006–1.290)

0.040*

Kurtosis

1.006 (1.000–1.011)

0.038*

1.009 (0.998–1.019)

0.113

1.011 (0.993–1.029)

0.242

Triangular index

0.961 (0.925–0.998)

0.039*

0.967 (0.938–0.997)

0.032*

0.978 (0.950–1.007)

0.133

NN50

0.993 (0.987–0.998)

0.008*

0.989 (0.981–0.998)

0.012*

0.988 (0.977–0.999)

0.031*

pNN50

0.978 (0.962–0.995)

0.009*

0.984 (0.971–0.997)

0.014*

0.987 (0.976–0.999)

0.027*

NN50n

–

–

0.982 (0.964–1.001)

0.065

0.952 (0.905–1.002)

0.059

pNN50n

–

–

0.974 (0.946–1.002)

0.069

0.951 (0.903–1.001)

0.054

Total power

1.000 (1.000–1.000)

0.031*

1.000 (1.000–1.000)

0.021*

1.000 (1.000–1.000)

0.072

VLF power

1.000 (1.000–1.000)

0.132

1.000 (1.000–1.000)

0.070

1.000 (1.000–1.000)

0.133

LF power

1.000 (1.000–1.000)

0.077

1.000 (1.000–1.000)

0.023*

1.000 (1.000–1.000)

0.063

HF power

1.000 (0.999–1.000)

0.002*

1.000 (1.000–1.000)

0.014*

1.000 (1.000–1.000)

0.074

LF power norm

1.001 (0.994–1.009)

0.738

0.999 (0.99–1.007)

0.733

0.994 (0.985–1.004)

0.248

HF power norm

0.999 (0.991–1.007)

0.738

1.001 (0.993–1.01)

0.733

1.006 (0.996–1.015)

0.248

LF/HF

1.034 (0.959–1.116)

0.381

1.014 (0.964–1.066)

0.592

1.001 (0.973–1.031)

0.923

Poincaré SD1

0.986 (0.975–0.997)

0.010*

0.988 (0.979–0.997)

0.011*

0.991 (0.983–0.999)

0.029*

Poincaré SD2

0.995 (0.990–1.000)

0.032*

0.997 (0.994–1.000)

0.032*

0.998 (0.996–1.000)

0.063

SampEn

0.813 (0.604–1.095)

0.173

0.730 (0.545–0.977)

0.035*

1.000 (1.000–1.000)

0.932

ApEn

1.645 (0.752–3.598)

0.213

2.319 (1.003–5.357)

0.049*

1.241 (0.463–3.327)

0.667

DFA, α1

0.953 (0.585–1.552)

0.846

1.031 (0.611–1.741)

0.908

0.968 (0.560–1.672)

0.907

DFA, α2

1.532 (0.773–3.034)

0.221

1.202 (0.782–1.848)

0.401

1.184 (0.934–1.500)

0.163

 

HR2V1

HR3V1

HR3V2

OR (95% CI)

p

OR (95% CI)

p

OR (95% CI)

p

Mean NN

0.999 (0.999–1.000)

0.023*

1.000 (0.999–1.000)

0.023*

1.000 (0.999–1.000)

0.023*

SDNN

0.996 (0.993–1.000)

0.034*

0.997 (0.995–1.000)

0.042*

0.997 (0.995–1.000)

0.034*

RMSSD

0.991 (0.984–0.998)

0.010*

0.992 (0.986–0.999)

0.016*

0.993 (0.986–0.999)

0.016*

Skewness

1.061 (0.980–1.149)

0.144

1.072 (0.978–1.176)

0.139

1.098 (0.982–1.227)

0.100

Kurtosis

1.007 (0.999–1.015)

0.082

1.006 (0.994–1.017)

0.333

1.010 (0.995–1.025)

0.195

Triangular index

0.981 (0.958–1.005)

0.119

0.982 (0.963–1.001)

0.065

0.974 (0.949–0.999)

0.040*

NN50

0.995 (0.991–0.999)

0.018*

0.996 (0.993–1.000)

0.052

0.992 (0.985–0.999)

0.035*

pNN50

0.984 (0.972–0.997)

0.020*

0.988 (0.977–1.000)

0.049*

0.988 (0.976–0.999)

0.035*

NN50n

0.989 (0.979–1.000)

0.043*

0.982 (0.964–1.000)

0.054

0.974 (0.943–1.007)

0.118

pNN50n

0.969 (0.939–0.999)

0.046*

0.947 (0.895–1.002)

0.058

0.960 (0.914–1.009)

0.109

Total power

1.000 (1.000–1.000)

0.048*

1.000 (1.000–1.000)

0.072

1.000 (1.000–1.000)

0.029*

VLF power

1.000 (1.000–1.000)

0.139

1.000 (1.000–1.000)

0.145

1.000 (1.000–1.000)

0.074

LF power

1.000 (1.000–1.000)

0.084

1.000 (1.000–1.000)

0.092

1.000 (1.000–1.000)

0.027*

HF power

1.000 (1.000–1.000)

0.005*

1.000 (1.000–1.000)

0.010*

1.000 (1.000–1.000)

0.022*

LF power norm

1.000 (0.991–1.008)

0.937

0.995 (0.985–1.006)

0.382

0.995 (0.986–1.005)

0.356

HF power norm

1.000 (0.992–1.009)

0.937

1.005 (0.994–1.015)

0.382

1.005 (0.995–1.015)

0.356

LF/HF

1.024 (0.970–1.080)

0.387

1.003 (0.973–1.033)

0.863

0.999 (0.971–1.029)

0.966

Poincaré SD1

0.987 (0.978–0.997)

0.010*

0.989 (0.980–0.998)

0.016*

0.989 (0.981–0.998)

0.016*

Poincaré SD2

0.997 (0.995–1.000)

0.039*

0.998 (0.996–1.000)

0.045*

0.998 (0.996–1.000)

0.037*

SampEn

0.854 (0.623–1.171)

0.328

0.802 (0.553–1.161)

0.242

0.709 (0.500–1.005)

0.053

ApEn

2.065 (0.842–5.064)

0.113

1.207 (0.499–2.922)

0.677

2.558 (0.906–7.222)

0.076

DFA, α1

0.888 (0.514–1.537)

0.672

1.039 (0.547–1.971)

0.907

1.004 (0.549–1.835)

0.991

DFA, α2

1.557 (0.782–3.098)

0.208

1.554 (0.780–3.093)

0.210

1.169 (0.764–1.789)

0.472

  1. HRV Heart rate variability, OR Odds ratio, CI Confidence interval, mean NN Average of R-R intervals, SDNN Standard deviation of R-R intervals, RMSSD Square root of the mean squared differences between R-R intervals, NN50 The number of times that the absolute difference between 2 successive R-R intervals exceeds 50 ms, pNN50, NN50 divided by the total number of R-R intervals; NN50n, the number of times that the absolute difference between 2 successive RRnI/RRnIm sequences exceeds 50 × n ms; pNN50n, NN50n divided by the total number of RRnI/RRnIm sequences; VLF Very low frequency, LF Low frequency, HF High frequency, SD Standard deviation, SampEn Sample entropy, ApEn Approximate entropy, DFA Detrended fluctuation analysis
  2. * p < 0.05
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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