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Table 3 Plasma levels of the 4 cardiovascular biomarkers under study before and after PMC, in the overall population and according to procedural success

From: Assessment of successful percutaneous mitral commissurotomy by MRproANP and sCD146

 

Whole population (N = 40)

Successful PMC (n = 30)

Unsuccessful PMC (n = 10)

Pre-PMC

Post-PMC

pvalue

Pre-PMC

Post-PMC

pvalue

Pre-PMC

Post-PMC

pvalue

BNP, pg/mL

182 [80–194]

132 [56–125]

0.028

184 [63–194]

122 [53–123]

0.03

176 [87–193]

161 [60–344]

0.62

NT-proBNP, pg/mL

1050[232–1171]

739 [219–909]

0.08

1067 [200–1171]

654 [141–706]

0.08

999 [311–1128]

994 [375–1951]

0.97

MR-proANP, nmol/mL

220 [142–273]

187 [130–224]

0.0025

219 [142–257]

179 [123–219]

0.0012

223 [139–284]

210 [133–347]

0.6

sCD146, ng/mL

379 [308–441]

343[277–416]

0.0081

370 [298–427]

327 [268–378]

0.002

406 [323–483]

389 [283–555]

0.7

  1. PMC percutaneous mitral commissurotomy. P-values are for the comparison before vs after by paired Student t test
  2. Reference values for middle-aged women: BNP < 100 pg/ml, NT-proBNP< 300 pg/mL, MR-proANP< 85 nmol/mL, sCD146 still under investigation, likely < 320 ng/mL