Table 4 Characteristics of Patients based on the PAH Diagnosis by RHC (n = 614)
Characteristics | No PAH (n = 203) | PAH (n = 411) | P value |
|---|---|---|---|
Age at Enrollment (years) [mean ± SD] | 32.2 ± 12.0 | 36.4 ± 12.9 | < 0.001 |
Gender [n (%)] | |||
Males | 42 (20.7) | 75 (18.2) | 0.469 |
Females | 161 (79.3) | 336 (81.8) | |
Body Mass Index [mean ± SD] | 20.2 ± 3.4 | 19.5 ± 6.9 | 0.136 |
Blood Pressure (mmHg) [mean ± SD] | |||
Systolic | 111.4 ± 15.1 | 110.7 ± 18.8 | 0.678 |
Diastolic | 73.4 ± 10.9 | 72.9 ± 11.9 | 0.698 |
Oxygen Saturation (%)[mean ± SD]a | 97.4 ± 3.2 | 94.8 ± 5.5 | < 0.001 |
6 Minute Walk Distance (meter)[mean ± SD]b | 393.9 ± 82.1 | 336.3 ± 99.7 | < 0.001 |
WHO Functional Class [n(%)]c | < 0.001 | ||
I | 122 (60.4) | 136 (34.0) | |
II | 70 (34.7) | 207 (51.8) | |
III-IV | 10 (5.0) | 57 (14.2) | |
Hemoglobin (g/dL) [mean ± SD]d | 13.5 ± 1.9 | 14.1 ± 2.2 | 0.006 |
Hematocrit (%) [mean ± SD]e | 40.2 ± 4.9 | 42.2 ± 6.5 | < 0.001 |
NTproBNP (pg/mL) [median (IQR)]f | 121.5 (57.1–218.1) | 774.0 (242.8–2022.3) | < 0.001 |
Congenital Anomalies [n (%)] | 0.005 | ||
ASD | 166 (81.8) | 367 (89.3) | |
VSD | 26 (12.8) | 17 (4.1) | |
PDA | 10 (4.9) | 21 (5.1) | |
Multiple defect | 1 (0.5) | 4 (1.0) | |
AP window | 0 (0) | 1 (0.2) | |
AVSD | 0 (0) | 1 (0.2) | |