Heparin-binding protein measurement improves the prediction of myocardial injury-related cardiogenic shock

Table 4 AUC for the predictors of MIRCS in age- and sex-matched patients

Variables	AUC	95%CI	Cut-off value	Sensitivity	Specificity
HBP_CS2	0.85	0.81–0.89	220	0.92	0.70
HBP_CPB2	0.71	0.64–0.77	140	0.88	0.46
HBP_CS2 - HBP_CPB2	0.85	0.81–0.90	30	0.71	0.99
(HBP_CS2 - HBP_CS1) / HBP_CS1	0.75	0.69–0.81	3.38	0.65	0.81
(HBP_CPB2 - HBP_CPB1) / HBP_CPB1	0.65	0.58–0.71	6.54	0.39	0.96
HPB_(CS-CPB) ratio	0.62	0.55–0.69	6.67	0.28	0.99
Peripheral arterial HBP at T0	0.64	0.59–0.68	114	0.85	0.44
Peripheral arterial HBP at T3	0.63	0.58–0.68	108	0.68	0.59
Peripheral arterial HBP at T24	0.71	0.67–0.75	87	0.84	0.53
Peripheral arterial HBP at T48	0.78	0.75–0.82	76	0.95	0.58
cTnT_CS2	0.76	0.70–0.82	1.71	0.65	0.82
Peripheral arterial cTnT
At 5 min after aortic declamping	0.70	0.64–0.77	0.42	0.92	0.41
At the end of surgery (T0)	0.75	0.69–0.81	0.78	0.64	0.70
At the 3rd hour after surgery (T3)	0.75	0.68–0.81	0.77	0.79	0.62
At the 24th hour after surgery (T24)	0.88	0.84–0.93	0.85	0.92	0.70
At the 48th hour after surgery (T48)	0.99	0.97–1.00	0.92	0.99	0.95
At the 72nd hour after surgery (T72)	0.96	0.94–0.98	0.76	0.99	0.82
Cardiac index wean from CPB	0.99	0.99–1.00	2.20	1.00	0.99
VIS wean from CPB	0.93	0.89–0.97	40	0.99	0.88
Lactate wean from CPB	0.92	0.88–0.97	4.45	0.99	0.92

AUC Area Under the Curve, HBP_CS Blood samples were obtained from coronary sinus, Time point 1 Before aortic cross-clamping, cTnT Cardiac troponin T, CI Confidence interval, HBP_CPB Blood samples were obtained from the arterial line of the CPB, Time point 2 5 min after aortic declamping, VIS Vasoactive-inotropic score, HPB_(CS-CPB) ratio = [(HBP_CS2 - HBP_CPB2)- (HBP_CS1 - HBP_CPB1)] / (HBP_CS1 - HBP_CPB1)

ISSN: 1471-2261