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Fig. 5 | BMC Cardiovascular Disorders

Fig. 5

From: Up-regulating autophagy by targeting the mTOR-4EBP1 pathway: a possible mechanism for improving cardiac function in mice with experimental dilated cardiomyopathy

Fig. 5

Modulating autophagy and cardiac function. (A) and (B) Cardiac function differed in the four groups, and the LVEF and FS significantly improved in the rapamycin group compared with the DCM group. (C) and (D) The LVEDD and LVEDV were significantly decreased in the 3-MA group compared with the DCM group. ††P < 0.01 and P < 0.05 vs Control, **P < 0.01, *P < 0.05, and #P < 0.05 vs DCM. Each group, n = 8

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