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Fig. 2 | BMC Cardiovascular Disorders

Fig. 2

From: Up-regulating autophagy by targeting the mTOR-4EBP1 pathway: a possible mechanism for improving cardiac function in mice with experimental dilated cardiomyopathy

Fig. 2

Transmission electron microscopy assessment for modulating autophagy. (A) Transmission electron microscopy indicated significant changes of autophagosomes in the four different groups. (B) Transmission electron microscopy showed that there was a significant increase of autophagosomes in the DCM group compared with the control group. Quantitative assessment demonstrated that autophagosomes were significantly increased in the rapamycin group, and they were decreased in the 3-MA group compared with the DCM group. †††P < 0.001 vs Control, ***P < 0.01 and #P < 0.05 vs DCM. The arrows indicated the double membrane autophagosomes in the different groups

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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