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Table 3 Laboratory parameters and disease activity of untreated TA patients with positive or negative ASO

From: Elevated antistreptolysin O titer is closely related to cardiac mitral insufficiency in untreated patients with Takayasu arteritis

 

ASO positive

n = 13

ASO negative

n = 61

P-Value

WBC(109/L)

7.0 ± 1.5

7.3 ± 2.2

0.643

NE(109/L)

4.7 ± 1.4

4.7 + 1.7

0.979

LY(109/L)

1.9 ± 0.6

2.1 ± 0.8

0.391

RBC(1012/L)

4.51 ± 0.41

4.5 ± 0.5

0.812

Hb (g/L)

122.8 ± 21.9

124.2 ± 19.3

0.809

PLT(109/L)

278.6 ± 107.2

265.4 ± 90.1

0.645

ALT (U/L)

13.7 ± 10.5

18.2 ± 14.3

0.289

Cr (μmol/l)

63.1 ± 12.8

61.2 ± 31.1

0.833

GLU (mmol/l)

5.0 ± 0.6

5.2 ± 1.1

0.612

HCY (μmol/l)

11.5 ± 3.5

13.9 ± 9.5

0.388

RF (IU/ml)

6.5 (4.0,10.6)

5.2 (3.1,11.7)

0.222

IL-6 (pg/ml)

16.2 (3.3, 29.4)

5.1 (2.3, 12.5)

0.157

TNF-α (pg/ml)

9.6 (5.8, 22.6)

20.3 (7.7, 48.7)

0.210

IgA (g/L)

3.2 ± 1.4

2.5 ± 1.3

0.086

IgG (g/L)

16.6 ± 4.1

12.9 ± 3.7

0.002

IgM (g/L)

1.5 ± 0.6

1.4 ± 1.0

0.823

IgE (g/L)

35.6 (14.3, 176.7)

17.0 (9.7, 87.3)

0.151

C3 (g/L)

1.3 ± 0.3

1.2 ± 0.2

0.188

C4 (g/L)

0.2 ± 0.1

0.2 ± 0.1

0.657

ESR (mm/1 h)

23.0 (9.0, 72.0)

18.0 (8.0, 39.0)

0.352

CRP (mg/L)

4.5 (1.8, 23.6)

2.2 (0.4, 21.5)

0.334

Kerr Score

2.5 ± 0.7

2.4 ± 0.7

0.484

ITAS

8.9 ± 6.0

8.2 ± 4.8

0.682

  1. Note: WBC white blood cell; LY lymphocyte; NE neutrophil; PLT platelet; RBC red blood cell; Hb hemoglobin; ALT alanine aminotransferase; Cr creatinine; GLU Glucose; HCY homocysteine; RF rheumatoid factor; IL interleukin; TNF tumor necrosis factor; Ig immunoglobulin; C3 complement 3; C4 complement 4; ESR erythrocyte sedimentation rate; CRP C-reactive protein