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Table 2 Echocardiographic parameters (short-axis view, M-mode images) of male and females animals at the end of the protocol

From: Sex differences in the evolution of left ventricle remodeling in rats with severe volume overload

ParametersShM (n = 8)ARM (n = 11)ShF (n = 8)ARF (n = 10)
AR severity, %NA66 ± 5NA73 ± 4
EDD, mm9.4 ± 0.212.6 ± 0.3*7.9 ± 0.111.1 ± 0.3*§
iEDD, mm/kg11.8 ± 0.416.1 ± 0.6*16.6 ± 0.726.3 ± 1.4*§
ESD, mm5.4 ± 0.38.4 ± 0.4*4.3 ± 0.17.5 ± 0.3*
iESD, mm/kg6.8 ± 0.410.6 ± 0.6*9.0 ± 0.117.6 ± 1.1*§
IVSW, mm1.6 ± 0.021.6 ± 0.031.2 ± 0.031.5 ± 0.03*
PW, mm1.9 ± 0.062.3 ± 0.061.6 ± 0.052.1 ± 0.05*
RWT, unitless0.36 ± 0.0110.32 ± 0.006*0.36 ± 0.0100.33 ± 0.010*
EF, %70 ± 260 ± 3*79 ± 159 ± 2*
E wave, cm/s89 ± 288 ± 480 ± 381 ± 4
A wave, cm/s49 ± 341 ± 239 ± 139 ± 3
E wave slope4278 ± 402 &4185 ± 3553954 ± 2464626 ± 371
  1. NA non applicable, EDD end-diastolic diameter, ESD end-systolic diameter, i indexed for body weight (kg), SW septum wall thickness, PW posterior wall thickness, RWT relative wall thickness, HR heart rate, bpm beats per minute. Values are expressed as the mean ± SEM. Group comparisons were made using two-way ANOVA followed by Holm-Sidak post-test. *: p < 0.05 vs. respective sham group. §: p < 0.05 between AR groups