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Table 1 Comparison with Other Previous Meta-analyses

From: Relationship between fluoroquinolones and the risk of aortic diseases: a meta-analysis of observational studies

Author/YearSingh S et al. 2017Noman AT et al. 2019Yu X et al. 2019Rawla P et al. 2019Current Meta-analysis
Number of observational studies23345
Number of participants1,893,5372,613,7132,613,7132,616,1392,829,385
Year of search strategy20172018201920182019
OR/RR of AA or ADAA (OR, 2.25; 95% CI,2.03–2.49)AA or AD (OR,2.04; 95% CI, 1.67–2.48)AA or AD (OR,2.20; 95% CI, 1.92–2.52)AA or AD (RR,2.14; 95% CI, 1.93–2.36)AA or AD (OR, 2.23; 95% CI, 1.80–2.77)
AD (OR, 2.07; 95% CI, 1.33–3.21)
AD (OR, 2.79; 95% CI,2.31–3.37)AD (OR, 2.25; 95% CI,1.42–3.56)
AA (OR, 1.74; 95% CI, 1.13–2.66)
GRADEmoderatemoderateNRmoderatemoderate
NNH618 (AA)1376NRNR1301
  1. AD aortic dissection, AA aortic aneurysm, GRADE Grading of Recommendations Assessment, Development, and Evaluation; NNH Number Need to Harm, NR not report