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Table 1 Comparison with Other Previous Meta-analyses

From: Relationship between fluoroquinolones and the risk of aortic diseases: a meta-analysis of observational studies

Author/Year

Singh S et al. 2017

Noman AT et al. 2019

Yu X et al. 2019

Rawla P et al. 2019

Current Meta-analysis

Number of observational studies

2

3

3

4

5

Number of participants

1,893,537

2,613,713

2,613,713

2,616,139

2,829,385

Year of search strategy

2017

2018

2019

2018

2019

OR/RR of AA or AD

AA (OR, 2.25; 95% CI,2.03–2.49)

AA or AD (OR,2.04; 95% CI, 1.67–2.48)

AA or AD (OR,2.20; 95% CI, 1.92–2.52)

AA or AD (RR,2.14; 95% CI, 1.93–2.36)

AA or AD (OR, 2.23; 95% CI, 1.80–2.77)

AD (OR, 2.07; 95% CI, 1.33–3.21)

AD (OR, 2.79; 95% CI,2.31–3.37)

AD (OR, 2.25; 95% CI,1.42–3.56)

AA (OR, 1.74; 95% CI, 1.13–2.66)

GRADE

moderate

moderate

NR

moderate

moderate

NNH

618 (AA)

1376

NR

NR

1301

  1. AD aortic dissection, AA aortic aneurysm, GRADE Grading of Recommendations Assessment, Development, and Evaluation; NNH Number Need to Harm, NR not report