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Table 2 Implant success rates, scores (CHA2DS2-VASc or CHADS2 and HAS-BLED), procedural data and anesthesia type

From: Systematic review on left atrial appendage closure with the LAmbre device in patients with non-valvular atrial fibrillation

 

CHA2DS2-VASc or CHADS2 Score

HAS-BLED Score

Implantion

Success (%)

Mean

procedure

time (min)

Mean

fluoroscopy

time (min)

Contrast

agent (ml)

Radiation dose

(cG*cm2)

Anesthesia type

(n=/%)

LVEF; (mean + SD)

Chen et al. (2019) [21]

CHA2DS2-VASc:

3.9 ± 1.5

4.1 + 1.0

100%

29.0 ± 10.1

3.5 ± 1.9

N/A

N/A

CS: n = 30/100%

N/A

Feng et al. (2019) [22]

CHADS2:

2.5 ± 1.1

2.7 + 0.8

100%

67.2 ± 11.9

18.6 ± 14.4

N/A

N/A

N/A

63.6 ± 4.4

Reinsch et al. (2018) [19]

CHA2DS2-VASc:

3.3 + 1.0

3.0 + 1.0

100%

65.1 ± 27.2

7.1 ± 2.7

< 50

N/A

CS: n = 11/100%

48.5+  9.1

Park et al. (2018) [18]

CHA2DS2-VASc:

4.0 + 1.6

3.2 + 1.3

100% a

33.9 ± 17.6

12.7 ± 4.8

97.2 ± 44

N/A

CS:

n = 23/38.3%

General:

n = 37/61.7%

58.0 ± 6.9

Kleinecke et al. (2018) [17]

CHA2DS2-VASc:

5.0 + 2.0

3.7 + 1.3

100%

23.4 ± 9.2

11.9 ± 4.1

96.2 ± 45.7

2718.4 ± 3835.3

N/A

56.4 ± 9.2

Cruz-Gonzalez et al. (2017) [20]

CHA2DS2-VASc:

5.4 + 1.0

3.3 + 0.8

100%

N/A

N/A

N/A

N/A

N/A

N/A

Chen et al. (2018) [9]

CHA2DS2-VASc:

3.9 + 1.5

4.1 + 1.0

100%

29.0 ± 10.1

3.5 ± 1.9

N/A

N/A

N/A

N/A

Zhou et al. (2017) [16]

CHA2DS2-VASc:

3.9 + 1.3

N/A

100%

49.7  ±   9.1

N/A

N/A

N/A

N/A

53.9 ± 6.1

Huang et al. (2017) [15]

CHA2DS2-VASc:

4.0 + 1.7

N/A

99.3%

(n = 152/153)

66.0 ± 24.0

N/A

N/A

N/A

General:

n = 152/100%

N/A

Jie et al. (2016) [14]

CHADS2:

2.4 ± 1.3

N/A

N/A

N/A

N/A

N/A

N/A

N/A

61.0 ± 8.5

Total /

Overall mean

CHA2DS2-VASc:

4.0 + 0.9

3.4 + 0.5

99.7%

(n = 348/349)

45.4 ± 18.7

9.6 ± 5.9

96.7 ± 0.7

 

CS:

n = 64/25.2%

General:

n = 189/74.4%

56.9 ± 5.3

  1. a: 1 enrolled patient did not undergo LAAC due to the anatomy of the interatrial septum not suitable for transseptal puncture
  2. Abbreviations
  3. CS Conscious sedation
  4. LVEF Left ventricular ejection fraction
  5. N/A Not available