Prevalence and risk factors of prolonged corrected QT interval in general Chinese population

Table 4 Sensitivity analysis of prolonged QTc interval and associated factors after exclusion of participants on medication in the past two weeks in multiple logistic regression (n = 5281)

Variables	ORs	95% CIs	P-value
Age (per 10 year increase)	1.216	1.127–1.311	< 0.001^*
Female gender	2.995	2.502–3.584	< 0.001^*
Race of Han^a	1.260	0.944–1.682	0.117
Current smoking status	0.948	0.808–1.112	0.511
Current drinking status	1.020	0.842–1.237	0.836
Education
Primary school or below	1.000 (reference)
Middle school	1.086	0.936–1.261	0.276
High school or above	1.294	1.029–1.626	0.027^*
Physical activity
Low	1.000 (reference)
Moderate	0.879	0.756–1.023	0.096
High	0.702	0.525–0.939	0.017^*
Family income (CNY/year)
≤ 5000	1.000 (reference)
5000–20,000	1.024	0.824–1.273	0.828
> 20,000	1.105	0.876–1.393	0.401
General obesity	1.089	0.891–1.330	0.407
Abdominal obesity	1.264	1.019–1.567	0.033^*
Hypertension	1.933	1.680–2.224	< 0.001^*
Diabetes	1.856	1.469–2.346	< 0.001^*
High TC	0.987	0.793–1.229	0.909
High TG	1.172	0.973–1.413	0.094
High LDL-C	1.142	0.843–1.547	0.391
Low HDL-C	1.214	0.987–1.492	0.066
Calcium (mmol/L) < 1.875	0.603	0.071–5.106	0.642
Potassium (mmol/L) < 3.5	2.224	1.118–4.426	0.023^*
Magnesium (mmol/L) < 0.7	1.893	0.323–11.098	0.479
History of heart disease^b	0.916	0.697–1.204	0.529

*P < 0.05 for the independent association between prolonged QTc interval and each factor after adjusting for the remaining factors
Abbreviations: CNY, China Yuan (1CNY = 0.15 USD); HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride; OR, odds ratio; QTc, corrected QT; 95% CI, 95% confidence interval
^aCompared with other ethnic minorities in China, such as Mongol and Manchu
^bIncluding coronary heart disease, arrythmia and heart failure

ISSN: 1471-2261