Prevalence of left ventricular diastolic dysfunction by cardiac magnetic resonance imaging in thalassemia major patients with normal left ventricular systolic function

Table 2 Cardiac magnetic resonance imaging parameters of study population

Variables	Total (n = 116)	Normal diastolic function (n = 92)	Diastolic dysfunction (n = 24)	p-value
LVEF (%)	63.59 ± 4.67	63.66 ± 4.47	63.33 ± 5.47	0.765
LVEDV (ml)	135.63 ± 34.15	132.17 ± 30.79	148.45 ± 43.12	0.093
LVESV (ml)	49.43 ± 14.20	47.88 ± 12.09	55.39 ± 19.81	0.087
LVMI (g/m²)	50.87 ± 13.40	49.52 ± 12.72	56.02 ± 14.91	*0.034*
LA area 2ch (mm²)	18.38 ± 4.61	17.64 ± 3.73	21.21 ± 6.38	*0.014*
LA length 2ch (mm)	45.01 ± 6.11	44.33 ± 5.42	47.63 ± 7.83	*0.018*
LA area 4ch (mm²)	20.59 ± 4.74	19.73 ± 3.84	23.92 ± 6.30	*0.004*
LA length 4ch (mm)	54.17 ± 6.79	53.11 ± 5.88	58.25 ± 8.48	*0.009*
LAVI (ml/m²)	50.37 ± 16.27	46.27 ± 10.48	66.06 ± 23.76	*0.001*
EPFR (ml/s)	383.26 ± 94.41	375.97 ± 82.55	411.19 ± 128.75	0.213
LPFR (ml/s)	210.30 ± 62.23	211.34 ± 59.56	206.31 ± 72.85	0.726
E velocity (cm/s)	61.76 ± 11.74	61.38 ± 10.86	63.23 ± 14.83	0.493
A velocity (cm/s)	42.21 ± 13.43	43.17 ± 13.96	38.54 ± 10.60	0.133
E/A	1.55 ± 0.42	1.49 ± 0.33	1.78 ± 0.60	*0.035*
Deceleration time (ms)	147.34 ± 32.95	147.94 ± 30.55	145.02 ± 41.58	0.701
Cardiac T2* (ms)	36.46 ± 8.96	36.65 ± 8.53	35.71 ± 10.61	0.649
Abnormal cardiac T2* (< 20 ms)	9 (7.76%)	7 (7.61%)	2 (8.33%)	1.00

A p-value< 0.05 indicates statistical significance (bold and italic)
Data presented as mean ± standard deviation or number and percentage
Abbreviations: LVEF Left ventricular ejection fraction, LVEDV Left ventricular end-diastolic volume, LVESV Left ventricular end-systolic volume, LVMI Left ventricular mass index, LA area 2ch Left atrial area from 2-chamber view, LA length 2ch Left atrial length from 2-chamber view, LA area 4ch Left atrial area from 4-chamber view, LA length 4ch Left atrial length from 4-chamber view, LAVI Left atrial volume index, EPFR Early peak filling rate, LPFR Late peak filling rate, E velocity Early diastolic filling velocity, A velocity Late atrial systolic filling velocity, E/A E/A ratio

ISSN: 1471-2261