Skip to main content

Table 3 Changes in Arterial Inflammation Activity: Index Vessel Analysis

From: Effects of ezetimibe/simvastatin 10/10 mg versus Rosuvastatin 10 mg on carotid atherosclerotic plaque inflammation

Characteristics

Ezetimibe /simvastatin (n = 25)

Rosuvastatin (n = 25)

p-value between groups

MDS TBR of index carotid artery

 Baseline

2.37 ± 0.46

2.23 ± 0.41

0.271

 Follow-up

2.07 ± 0.29

2.09 ± 0.46

0.889

 Nominal change

−0.30 ± 0.43

−0.15 ± 0.40

0.197

p-value compared with baseline

0.002

0.077

 

 Percent change (primary endpoint)

−10.22 ± 17.49

−5.84 ± 15.78

0.357

Whole vessel TBR of index carotid artery

 Baseline

2.00 ± 0.0.39

1.94 ± 0.31

0.537

 Follow-up

1.81 ± 0.26

1.83 ± 0.35

0.772

 Nominal change

−0.19 ± 0.38

− 0.11 ± 0.38

0.419

p-value compared with baseline

0.017

0.168

 

 Percent change

−6.81 ± 19.06

−3.95 ± 17.01

0.579

MDS TBR of aorta

 Baseline

2.58 ± 0.45

2.57 ± 0.45

0.912

 Follow-up

2.27 ± 0.34

2.35 ± 0.46

0.459

 Nominal change

−0.31 ± 0.44

−0.21 ± 0.52

0.466

p-value compared with baseline

0.002

0.052

 

 Percent change

−10.35 ± 16.24

−6.80 ± 18.36

0.473

Whole vessel TBR of aorta

 Baseline

2.47 ± 0.43

2.47 ± 0.45

0.959

 Follow-up

2.19 ± 0.33

2.26 ± 0.45

0.507

 Nominal change

−0.29 ± 0.43

−0.20 ± 0.52

0.549

p-value compared with baseline

0.003

0.063

 

 Percent change

−9.580 ± 16.45

−6.58 ± 19.04

0.526

  1. Nominal change is calculated as follow-up minus baseline, and percent change as (follow-up minus baseline)/baseline×100. MDS Most diseased segment, TBR Tissue blood ratio