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Table 2 Baseline angiographic and VH-IVUS findings of the intermediate lesions

From: Long-term clinical outcomes in patients with untreated non-culprit intermediate coronary lesion and evaluation of predictors by using virtual histology-intravascular ultrasound; a prospective cohort study

Variables

MACE

n = 27 (30.3%)

no MACE

n = 62 (69.7%)

P value

Location

  

0.871

 LM, n (%)

2 (7.4)

8 (12.9)

 

 LAD, n (%)

16 (59.3)

30 (48.4)

 

 LCX, n (%)

4 (14.8)

13 (21.0)

 

 RCA, n (%)

5 (18.5)

10 (16.1)

 

 Ramus intermedius, n (%)

0 (0)

1 (1.6)

 

Diameter stenosis, % (QCA)

47.6 ± 8.1

42.2 ± 1.2

0.012

Grayscale IVUS

 Diameter stenosis, %

29.1 ± 10.9

26.7 ± 8.1

0.314

 Lesion length, mm

13.1 ± 6.6

13.9 ± 7.7

0.609

 Area stenosis, %

39.2 ± 16.7

35.7 ± 13.7

0.321

 Minimal luminal area, mm2

4.9 ± 1.6

5.8 ± 2.5

0.073

 Minimal luminal diameter, mm

2.3 ± 0.3

2.4 ± 0.5

0.130

 Plaque burden, %

66.0 ± 8.6

61.6 ± 9.9

0.045

 Reference area, mm2

8.4 ± 2.6

8.6 ± 3.2

0.806

 Lumen volume, mm3

92.9 ± 43.3

99.3 ± 57.0

0.607

 Plaque volume, mm3

119.8 ± 94.1

114.7 ± 76.8

0.790

 Remodeling index

1.0 ± 0.1

1.0 ± 0.1

0.814

VH-IVUS

 TCFA, n (%)

7 (25.9)

19 (30.6)

0.653

 Fibrous area, mm2

4.4 ± 2.5

4.0 ± 2.3

0.472

 Fibrofatty area, mm2

1.5 ± 1.8

0.8 ± 0.8

0.047

 Dense calcium area, mm2

0.5 ± 0.5

0.5 ± 0.5

0.547

 Necrotic core area, mm2

1.2 ± 1.2

1.1 ± 0.9

0.774

 Percent fibrous area, %

59.0 ± 13.9

61.2 ± 14.2

0.511

 Percent fibrofatty area, %

15.6 ± 13.1

11.0 ± 7.8

0.101

 Percent dense calcium area, %

7.6 ± 6.4

9.3 ± 9.3

0.394

 Percent necrotic core area, %

17.9 ± 14.0

18.4 ± 10.7

0.845

 Fibrous volume, mm3

44.2 ± 46.6

42.7 ± 34.5

0.866

 Fibrofatty volume, mm3

13.2 ± 18.0

8.8 ± 11.2

0.166

 Dense calcium volume, mm3

5.5 ± 6.0

6.2 ± 6.2

0.639

 Necrotic core volume, mm3

11.1 ± 10.4

11.8 ± 9.7

0.784

 Percent fibrous volume, %

61.2 ± 12.1

61.0 ± 11.5

0.966

 Percent fibrofatty volume, %

14.9 ± 9.6

11.7 ± 7.4

0.093

 Percent dense calcium volume, %

7.9 ± 6.8

9.3 ± 7.6

0.413

 Percent necrotic core volume, %

16.0 ± 10.4

17.9 ± 9.7

0.400

  1. VH-IVUS virtual histology-intravascular ultrasound, MACE major adverse cardiovascular events, LM left main coronary artery, LAD left anterior descending artery, LCX left circumflex artery, RCA right coronary artery, QCA quantitative coronary angiography, TCFA thin-cap fibroatheroma