Table 1 Clinical, biochemical, behavioral and socio-demographic characteristics of blood donors stratified according to estimated 10-year cardiovascular disease risk
Overall | Low CRS N (%) = 884 (78.3) | Moderate/High CRS N (%) = 245 (21.7) | p-value | |
|---|---|---|---|---|
Age, n (%) [N = 1,447] | < 0.001 | |||
18-29a | 120 (8.3) | – | – | |
30–40 | 298 (20.6) | 183 (21) | 1 (0.4) | |
41–50 | 638 (44.1) | 525 (59.4) | 47 (19.2) | |
51–60 | 322 (22.3) | 160 (18.1) | 146 (59.6) | |
> 60 | 67 (4.6) | 16 (1.8) | 51 (20.4) | |
Gender, n(%) | < 0.001 | |||
Male | 886 (61.2) | 462 (52.3) | 225 (92) | |
Female | 561 (38.8) | 422 (47.7) | 20 (8.2) | |
Marital Status, n (%) [N = 1,420] | 0.001 | |||
Unmarried | 331 (23.3) | 131 (15) | 17 (7) | |
Married | 972 (68.4) | 663 (75.9) | 195 (81.2) | |
Divorced/separated | 105 (7.4) | 74 (8.5) | 22 (9.2) | |
Widow/er | 12 (0.85) | 5 (0.6) | 6 (2.5) | |
Educational attainment, n (%) [1,385] | 0.007 | |||
HEA | 1.098 (79.3) | 671 (78.8) | 167 (70.5) | |
LEA | 287 (20.7) | 181 (21.2) | 70 (29.5) | |
Smokers, n (%) [N = 1,436] | < 0.001 | |||
Yes | 299 (20.8) | 135 (15.3) | 72 (29.5) | |
No | 1.137 (79.2) | 746 (84.7) | 172 (70.5) | |
Cigarettes/day, mean (SD) | 1.9 (4.9) | 1.4 (4.2) | 3 (5.8) | < 0.001 |
Regular physical activity, n (%) [N = 1,436] | 0.177 | |||
Yes | 299 (20.8) | 509 (57.7) | 129 (52.9) | |
No | 1.137 (79.2) | 373 (42.3) | 115 (47.1) | |
Physical activity/week, mean (SD) | 1.6 (1.7) | 1.6 (1.7) | 1.3 (1.5) | 0.038 |
Anthropometric indices, mean (SD) | ||||
BMI (Kg/m2), [N = 1,435] | 25.8 (3.9) | 25.6 (3.7) | 27.1 (3.5) | < 0.001 |
Waist circumference (cm), [N = 1,242] | 91.3 (11.8) | 90.3 (10.8) | 97 (10.7) | < 0.001 |
CVD RF measurements, mean (SD) | ||||
Fasting Glucose (mmol/l), [N = 1,415] | 5.40 (12.5) | 5.37 (12.4) | 5.74 (12.7) | < 0.001 |
Systolic Blood Pressure (mm/Hg), [1,396] | 120.4 (7.2) | 119.4 (6.1) | 125.6 (8.7) | < 0.001 |
Diastolic Blood Pressure (mm/Hg) | 75.6 (6.2) | 75 (5.9) | 79.5 (5.7) | < 0.001 |
Total Cholesterol (mmol/l), [1,424] | 5.11 (35) | 5.11 (33.7) | 5.56 (35.5) | < 0.001 |
Triglycerides (mmol/l) | 1.16 (75) | 1.07 (58.9) | 1.63 (100.1) | < 0.001 |
HDL Cholesterol (mmol/l), [N = 1,360] | 1.42 (13.3) | 1.46 (13.4) | 1.25 (11) | < 0.001 |
LDL Cholesterol (mmol/l), [N = 1,284] | 3.58 (36.2) | 3.56 (34.4) | 4.07 (35.2) | < 0.001 |
Biomarkers, mean (SD) | ||||
HCY (μmol/l), [N = 1,038] | 11 (4.4) | 10.7 (4.3) | 12.5 (4.7) | < 0.001 |
Lp (a) (mg/dl), [N = 774] | 20.3 (24.4) | 21.5 (24.6) | 19.4 (25.8) | 0.345 |
Biomarkers prevalence, n (%) | ||||
HCY ≥ 15 μmol/l | 118 (11.4) | 65 (9.7) | 39 (18.7) | < 0.001 |
Lp (a) > 30 mg/dl | 172 (22.4) | 116 (24.2) | 35 (20.3) | 0.308 |
Health-Related Quality of life, mean (SD), [1,189] | ||||
PCS | 52.6 (5.6) | 52.4 (5.7) | 52.1 (5.8) | 0.575 |
MCS | 48.6 (9.4) | 48.6 (9.4) | 49.2 (8.8) | 0.398 |