Table 5 Procedural outcomes by access route

X_w/X_wo

p-value

X_w/X_wo

p-value

X_w/X_wo

p-value

 Valve size

0.038

0.005

0.001

  20–23 mm

37.5 / 31.4

29.5 / 30.7

26.6 / 30.8

  26 mm

23.2 / 39.3

49.2 / 40.9

49.5 / 44.9

  29 mm

39.3 / 29.3

21.3 / 28.5

23.9 / 24.4

 Quantity contrast agent used (mL)

131 / 120

0.240

85 / 80

0.681

94 / 80

0.008

 Effective orifice area post-surgery

1.40 / 1.65

0.203

2.10 / 2.00

0.222

1.80 / 1.82

0.809

 Indexed effective orifice area

0.71 / 0.87

0.175

1.17 / 1.04

0.137

1.04 / 1.00

0.857

 AV mean PG post-surgery

12 / 11

0.138

4 / 5

0.641

9 / 10

0.863

 Paravalvular regurgitation

0.001

< 0.001

< 0.001

  None/trace

85.7 / 86.0

78.7 / 84.7

76.6 / 80.8

  Mild

14.3 / 13.2

21.3 / 14.6

19.4 / 19.2

  Moderate

0 / 0.7

0 / 0.7

3.6 / 0

  Severe

0 / 0

0 / 0

0.5 / 0

X_w/X_wo

OR (95% CI)

X_w/X_wo

OR (95% CI)

X_w/X_wo

OR (95%CI)

 Post-delivery balloon dilation (%)

30.4 / 15.7

0.43 (0.21–0.89)

14.8 / 9.5

1.65 (0.65–4.07)

22.5 / 25.6

0.84 (0.47–1.56)

 Access complications (%)

0 / 5

n.a.

0 / 0.7

n.a.

1.4 / 0

n.a.

 Hemodynamic instability (%)

3.6 / 0.7

0.19 (0.01–2.07)

6.6 / 4.4

0.65 (0.18–2.63)

n.c.

n.a.

 Catecholamine use (%)

1.8 / 0.7

0.4 (0.02–10.12)

32.8 / 17.5

0.44 (0.22–0.87)

n.c.

n.a.

 Device success (%)

92.9 / 98.6

5.31 (1.01–39.12)

100 / 100

n.a.

98.6 / 98.7

0.95 (0.05–7.53)

 Second valve needed (%)

0 / 0.7

n.a.

0 / 0

n.a.

1.8 / 2.6

0.7 (0.13–5.1)

 Conversion to surgery (%)

0 / 2.9

n.a.

0 / 1.5

n.a.

1.7 / 0

n.a.

 Device malfunction (%)

0 / 0

n.a.

0 / 0.7

n.a.

0.9 / 0

n.a.

 Atrioventricular block (%)

3.6 / 2.1

0.59 (0.1–4.58)

1.6 / 1.5

0.89 (0.08–19.34)

5 / 0

n.a.

 Aortic root rupture (%)

0 / 0

n.a.

0 / 0

n.a.

0.5 / 0.0

n.a.

 Correct positioning of a single prosthetic valve into the proper anatomical location (%)

100 / 100

n.a.

100 / 100

n.a.

98.6 / 98.7

1.05(0.13–21.5)

 Intended performance of the prosthetic valve (%)

92.9 / 98.6

5.31 (1.01–39.1)

100 / 100

n.a.

99.1 / 98.7

0.7 (0.07–15.2)