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Fig. 7 | BMC Cardiovascular Disorders

Fig. 7

From: Downregulation of long non-coding RNA nuclear enriched abundant transcript 1 promotes cell proliferation and inhibits cell apoptosis by targeting miR-193a in myocardial ischemia/reperfusion injury

Fig. 7

Rescue experiments. Cell proliferation rate was decreased in in OGD/R&miR-inhibitor group compared to OGD/R&NC-inhibitor group at 48 h and 72 h, but it was reduced in OGD/R&sh-NEAT1&miR-inhibitor group compared to OGD/R&sh-NEAT1&NC-inhibitor group at 48 h and 72 h. In addition, cell apoptosis rate was elevated in OGD/R&miR-inhibitor group compared to OGD/R&NC-inhibitor group at 72 h and increased in OGD/R&sh-NEAT1&miR-inhibitor group compared to OGD/R&sh-NEAT1&NC-inhibitor group at 72 h. Lnc-NEAT1, long non-coding RNA nuclear enriched abundant transcript 1. OGD/R, oxygen and glucose deprivation followed by reperfusion. p < 0.05 was considered significant. **p < 0.01, OGD/R&miR-inhibitor group vs. OGD/R&NC-inhibitor group; *p < 0.05, OGD/R&miR-inhibitor group vs. OGD/R&NC-inhibitor group; ##p < 0.01, OGD/R&sh-NEAT1&miR-inhibitor group vs. OGD/R&sh-NEAT1&NC-inhibitor group; #p < 0.05, OGD/R&sh-NEAT1&miR-inhibitor group vs. OGD/R&sh-NEAT1&NC-inhibitor group

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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