CD36 gene polymorphism rs1761667 (G > A) is associated with hypertension and coronary artery disease in an Iranian population

Table 1 Demographics and biochemical parameters of subjects among four groups

Variables	H-Tens (N = 52)	CAD + H-Tens (N = 57)	CAD (N = 65)	Ctrl (N = 64)	P-value
Age, years	54.69 ± 9.05	56.52 ± 11.00	56.20 ± 9.78	54.00 ± 10.40	0.424
Sex (m/f)	27/25	44/13	54/11	39/26	< 0.001^b
BMI (kg/m²)	27.02 ± 5.48	24.92 ± 4.48	24.52 ± 4.37	25.08 ± 5.12	0.057^c
FBS (mg/dl)	94.23 ± 12.68	95.30 ± 18.95	94.30 ± 15.13	95.56 ± 14.58	0.860^c
TG (mg/dl)	116.35 ± 58.33	109.57 ± 56.25	111.90 ± 58.06	107.92 ± 37.93	0.788^c
TC (mg/dl)	143.13 ± 32.82	136.38 ± 34.17	144.03 ± 38.52	149.05 ± 45.97	0.492^c
HDL-c (mg/dl)	38.21 ± 9.72	37.11 ± 9.62	38.92 ± 10.70	41.63 ± 10.32	0.061^a
LDL-c (mg/dl)	79.84 ± 30.91	77.46 ± 27.65	83.01 ± 31.80	83.43 ± 41.38	0.938^c
Na (mmol/l)	139.60 ± 3.23	139.27 ± 3.13	139.70 ± 2.95	139.18 ± 2.99	0.702^c
K (mmol/l)	4.34 ± 0.44	4.20 ± 0.36	4.34 ± 0.43	4.31 ± 0.44	0.311^c
Cr (mg/dl)	0.98 ± 0.22	1.07 ± 0.20	1.10 ± 0.19	1.04 ± 0.23	0.012^c
Urea (mg/dl)	35.48 ± 10.36	35.39 ± 9.10	36.28 ± 10.24	34.76 ± 12.67	0.753^c
DBP (mmHg)	74.54 ± 9.32	72.73 ± 12.06	70.08 ± 8.03	75.73 ± 8.28	0.017^c
SBP (mmHg)	123.02 ± 14.58	121.25 ± 13.25	115.33 ± 11.61	122.14 ± 14.21	0.002^c

H-Tens Hypertension, CAD + H-Tens Coronary Artery Disease and Hypertension, CAD Coronary Artery Disease, Ctrl Control; BMI Body mass index, FBS Fasting blood sugar, TC Total cholesterol, TG Triglycerides, HDL-c High-density lipoprotein cholesterol, LDL Low-density lipoprotein cholesterol, Na Sodium, K potassium, Cr Creatinine, SBP Systolic Blood Pressure, DBP Diastolic Blood Pressure. Continuous and categorical values are presented as mean ± SD and number, respectively
^aANOVA followed by post-hoc Tukey test
^bchi-square test
^cKruskal-Wallis followed by post-hoc Mann-Whitney U-test

ISSN: 1471-2261