Skip to main content

Table 1 Clinical characteristics of study population according to CHA2DS2-VASC

From: CHA2DS2-VASC score as a preprocedural predictor of contrast-induced nephropathy among patients with chronic total occlusion undergoing percutaneous coronary intervention: a single-center experience

Variable

CHA2DS2-VASc Score

p-value

low risk (1 point, n = 64)

intermediate risk (2–3 points, n = 135)

high risk (≥4 points, n = 40)

Age (years), mean (SD)

53.0 ± 7.5

59.1 ± 6.4

67.9 ± 7.9

P<0.001

Gender (female), n(%)

0

63 (47.4)

19 (47.5)

P<0.001

Body mass index (Kg/m2)

25.3 ± 1.8

24.4 ± 2.9

24.3 ± 2.6

0.04

Diabetes Mellitus, n(%)

0

20 (14.8)

20 (50.0)

P<0.001

Hypertension, n(%)

0

34 (25.2)

27 (67.5)

P<0.001

Stroke history, n(%)

0

2 (1.5)

6 (15.0)

P<0.001

Current smoker, n(%)

17 (26.6)

45 (33.3)

8 (20.0)

0.23

Previous MI, n(%)

19 (29.2)

46 (34.1)

11 (25.5)

0.67

Systolic blood pressure (mmHg)

119.1 ± 13.7

121.8 ± 12.1

124.6 ± 14.2

0.28

Diastolic blood pressure (mmHg)

74.7 ± 10.0

74.2 ± 9.3

72.4 ± 5.8

0.015

Pulse pressure (mmHg)

44.4 ± 10.2

47.6 ± 9.7

52.2 ± 12.2

0.001

LVEF

0.51 ± 0.04

0.45 ± 0.06

0.43 ± 0.04

P<0.01

NYHA 2–3 on admision

0

20 (14.8)

17 (42.5)

P<0.01

Total Cholesterol (mmol/L)

4.2 ± 1.0

4.3 ± 1.1

4.3 ± 0.9

0.70

LDL-C (mmol/L)

2.6 ± 0.6

2.5 ± 0.6

2.7 ± 0.6

0.23

HDL-C (mmol/L)

1.1 ± 0.3

1.1 ± 0.3

1.2 ± 0.4

0.25

Triglyceride (mmol/L)

1.6 ± 1.2

1.5 ± 1.3

1.3 ± 0.8

0.59

Fasting Glucose (mmol/L)

5.3 ± 0.5

5.5 ± 0.8

5.8 ± 1.0

0.027

eGFR baseline (ml/min/1.73m2)

102.0 ± 13.8

92.8 ± 17.0

89.5 ± 17.6

P<0.001

eGFR after PCI (ml/min/1.73m2)

98.4 ± 14.2

87.4 ± 19.5

76.2 ± 21.3

P<0.001

First Day Creatinine (μmol/l)

68.8 ± 19.2

69.5 ± 16.9

65.0 ± 17.6

0.37

Uric acid (μmol/l)

330.3 ± 69.9

330.8 ± 69.8

336.1 ± 75.6

0.90

Total amount of conrrast (ml)

181.8 ± 63.5

241.8 ± 104.0

320.3 ± 92.5

P<0.001

Total time of procedure (min)

74.4 ± 45.6

96.1 ± 47.7

129.7 ± 51.6

P<0.001

The retrograde approach, n(%)

14 (21.5)

29 (21.5)

14 (35.0)

0.19

Transradial + transfemoral approach, n(%)

21 (32.8)

42 (31.1)

17 (42.5)

0.40

IABP, n(%)

4 (6.3)

6 (4.4)

7 (17.5)

0.02

IVUS, n(%)

4 (6.3)

9 (6.7)

5 (12.5)

0.42

Stent number

1.9 ± 0.3

2.3 ± 0.6

2.6 ± 1.1

P<0.001

Glycoprotein IIb/IIIa receptor inhibitor, n(%)

12 (18.8)

24 (17.8)

13 (32.5)

0.12

CIN

4 (6.3)

20 (14.8)

15 (37.5)

P<0.001

  1. MI myocardial infarction, LVEF left ventricular ejection fraction, NYHA New York Heart Association (classification), LDL-C low density lipoprotein-cholesterol, HDL-C high density lipoprotein-cholesterol, IABP intra-aortic balloon pump, IVUS intravascular ultrasound, CIN contrast induced nephropathy