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Table 4 Significant co-variates associated with intermediate groups in different regions

From: Regional variations in trajectories of long-term readmission rates among patients in England with heart failure

Intermediate group

OR [95% CI]

P value

London

 Hypertension

2.80 [1.95–4.01]

0.003

 Chronic renal disease

1.65 [1.27–2.14]

0.05

 Chronic respiratory disease

1.63 [1.27–2.10]

0.05

 Number of patients with previous GP visit for HF medication review

0.51 [0.37–0.71]

0.04

 Older age

0.35 [0.26–0.46]

0.002

East of England

 Diabetes

0.32 [0.18–0.54]

0.03

 Chronic respiratory disease

0.32 [0.19–0.54]

0.03

 Chronic renal disease

0.21 [0.12–0.37]

0.005

North-East

 Cardiac congenital conditions

4.31 [2.51–7.39]

0.007

 Hypertension

3.90 [3.32–4.57]

<  0.001

 Ischaemic heart disease

2.36 [1.79–3.13]

0.002

 Mood disorders

2.32 [2.01–2.66]

<  0.001

 Chronic renal diseases

2.03 [1.84–2.25]

<  0.001

 Valvular heart disease

1.95 [1.73–2.20]

<  0.001

 Cardiac arrhythmias

1.93 [1.75–2.14]

<  0.001

 Dementia

1.80 [1.57–2.08]

<  0.001

 Respiratory conditions

1.54 [1.39–1.70]

<  0.001

 Anaemia

1.54 [1.38–1.72]

<  0.001

 Stroke

1.35 [1.20–1.52]

0.012

 Atrial fibrillation

1.31 [1.19–1.45]

0.0099

 History of smoking

0.87 [0.81–0.93]

0.048

 Number of patients with increased out-of-hours GP visits (>90th percentile)

0.64 [0.55–0.75]

0.0028

 GP visit for renal monitoring

0.62 [0.53–0.72]

0.0016

 Number of patients with previous GP visit for HF medication review

0.62 [0.51–0.76]

0.017

 Older age

0.57 [0.53–0.60]

<  0.001

  > 3 hospital admissions in preceding year of diagnosis of HF vs. <=2)

0.34 [0.25–0.45]

<  0.001

 HF diagnosis as an inpatient

0.32 [0.28–0.37]

<  0.001

North-West

 Hypertension

11.36 [5.53–23.34]

<  0.001

 Chronic renal disease

5.81 [4.10–8.25]

<  0.001

 Cardiac arrhythmias

4.26 [3.10–5.87]

<  0.001

 Atrial fibrillation

2.72 [1.95–3.78]

0.003

 Mood disorder

2.61 [1.79–3.82]

0.012

 Number of patients with GP visit for flu vaccination

2.51 [1.80–3.49]

0.005

 Anaemia

1.97 [1.46–2.66]

0.033

 Presentation of atypical signs and symptoms before the diagnosis of HF

0.42 [0.28–0.64]

0.04

 HF diagnosis as an inpatient

0.25 [0.16–0.38]

0.001

 Older age

0.19 [0.13–0.27]

<  0.001

South-Central

 Chronic respiratory disease

0.36 [0.23–0.56]

0.024

 Cardiac arrhythmia

0.25 [0.15–0.43]

0.011

 Dementia

0.24 [0.14–0.44]

0.016

 Hypertension

0.22 [0.13–0.37]

0.004

 Chronic renal disease

0.17 [0.11–0.29]

<  0.001

South-East

 Hypertension

5.37 [2.97–9.68]

0.004

 Older age

0.23 [0.16–0.35]

<  0.001

 HF diagnosis as an inpatient

0.15 [0.11–0.21]

<  0.001

West-Midlands

 Hypertension

3.16 [2.25–4.44]

<  0.001

 Chronic respiratory disease

2.01 [1.55–2.61]

0.007

 Atrial fibrillation

1.86 [1.42–2.44]

0.023

 Valvular heart disease

1.82 [1.36–2.44]

0.042

 HF diagnosis as an inpatient

0.42 [0.32–0.57]

0.003

 Older age

0.36 [0.27–0.48]

<  0.001

South-West

 Hypertension

4.81 [3.39–6.82]

<  0.001

 Atrial fibrillation

1.80 [1.38–2.36]

0.03

 HF diagnosis as an inpatient

0.39 [0.27–0.56]

0.01

 Number of patients with previous GP visit for HF medication review

0.28 [0.19–0.41]

<  0.001