Impaired myocardial perfusion is associated with increasing end-systolic- and end-diastolic volumes in patients with non-ischemic systolic heart failure: a cross-sectional study using Rubidium-82 PET/CT

Table 5 Analyses of MBF and ESVI and EDVI

	Univariable		Multivariable^a
	MBF^b (95% CI)	P-value	MBF^b (95% CI)	P-value
Rest
ESVI (10 ml/m²)	−0.02 (− 0.03 to − 0.004)	0.01	−0.003 (− 0.03 to 0.02)	0.81
EDVI (10 ml/m²)	−0.02 (− 0.03 to − 0.002)	0.03	0.00 (− 0.02 to 0.02)	0.99
Rest adjusted for rate-pressure product
ESVI (10 ml/m²)	−0.02 (− 0.04 to − 0.002)	0.03	−0.01 (− 0.03 to 0.04)	0.73
EDVI (10 ml/m²)	−0.02 (− 0.03 to 0.00)	0.054	0.01 (− 0.02 to 0.03)	0.67
Stress
ESVI (10 ml/m²)	−0.10 (− 0.14 to − 0.06)	< 0.0001	−0.07 (− 0.14 to − 0.001)	0.048
EDVI (10 ml/m²)	−0.10 (− 0.13 to − 0.06)	< 0.0001	−0.06 (− 0.12 to 0.00)	0.052

^aAll multivariable values shown are adjusted for sex, age, hypertension, diabetes, NT-pro-BNP, LV bundle branch block, LV ejection fraction, atrial fibrillation during scan, increases in heart rate from rest to stress and coronary calcium score. ^bChange in MBF (ml/g/min). ESVI end-systolic volume index, EDVI end-diastolic volume index

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