Table 2 associations of clinical and healthcare provider factors with suboptimal statin adherence and non-persistence in patients post ASCVD discharge

  Age at index date > 75 vs. ≤75 (y)

1.10

(1.08–1.12)^‡

−0.026

(0.002)^‡

1.11

(1.09–1.13)^‡

  Female vs. male

0.96

(0.95–0.98)^†

0.007

(0.002)^‡

1.00

(0.99–1.02)

  Used one year prior to ASCVD

0.72

(0.71–0.74)^‡

0.069

(0.002)^‡

0.89

(0.86–0.93)^‡

  Used during hospitalization

0.93

(0.91–0.95)^‡

0.015

(0.002)^‡

0.74

(0.72–0.75)^‡

 Ischemic stroke

Ref.

(0.98–1.07)

Ref.

Ref.

 AMI without PTCA/CABG

1.03

(0.63–0.67)^‡

0.002

(0.004)

1.06

(1.02–1.11)†

 AMI receiving revascularization

0.65

(0.69–0.73)^‡

0.087

(0.003)^‡

0.69

(0.67–0.71)‡

CHD receiving revascularization

0.71

(0.98–1.07)

0.075

(0.003)^‡

0.71

(0.69–0.73)‡

 Renal disease

1.29

(1.25–1.33)^‡

−0.043

(0.003)^‡

1.21

(1.17–1.24)^‡

 Liver disease

1.10

(1.07–1.14)^‡

−0.013

(0.003)^‡

1.09

(1.06–1.12)^‡

 Depression

1.10

(1.06–1.14)^‡

−0.015

(0.004)^‡

1.09

(1.06–1.12)^‡

 COPD

1.07

(1.04–1.10)^‡

−0.012

(0.003)^†

1.07

(1.04–1.09)^‡

 Dementia

1.06

(1.01–1.12)

−0.018

(0.005)^†

1.05

(1.00–1.10)^†

 Transient ischemic attack

0.99

(0.95–1.03)

0.002

(0.004)

1.01

(0.97–1.05)

 Ischemic heart disease

0.99

(0.97–1.01)

0.004

(0.002)^†

0.98

(0.96–1.00)

 Cancer

1.00

(0.96–1.03)

0.004

(0.003)^†

0.98

(0.95–1.01)

 Hyperlipidemia

0.93

(0.91–0.95)^‡

0.022

(0.002)^‡

0.93

(0.91–0.95)^‡

 Insulin

1.15

(1.12–1.18)^‡

−0.020

(0.002)^‡

1.11

(1.08–1.13)^‡

 Digitalis

1.12

(1.08–1.17)^‡

−0.022

(0.004)^‡

1.10

(1.06–1.15)^‡

 OADs

1.05

(1.03–1.07)^‡

−0.007

(0.002)^‡

1.09

(1.07–1.11)^‡

 ACEIs

1.05

(1.03–1.07)^‡

−0.009

(0.002)^‡

1.05

(1.03–1.07)^‡

 Diuretics

1.05

(1.03–1.07)^‡

−0.011

(0.002)^‡

1.05

(1.03–1.07)^‡

 CCBs

1.02

(1.00–1.04)

−0.003

(0.002)

1.04

(1.03–1.06)^‡

 Anticoagulants

0.99

(0.96–1.02)

0.003

(0.003)

0.95

(0.93–0.98)^‡

 β-blockers

0.95

(0.93–0.96)^‡

0.008

(0.002)^‡

0.97

(0.95–0.98)^‡

 ARBs

0.95

(0.93–0.97)^‡

0.008

(0.002)^‡

0.96

(0.94–0.97)^‡

 Antiplatelet agents

0.94

(0.92–0.96)^‡

0.010

(0.002)^‡

0.93

(0.92–0.95)^‡

 Dosage: moderate vs. low

0.96

(0.94–0.97)^‡

0.010

(0.002)^‡

0.95

(0.93–0.96)^‡

 Dosage: high vs. low

1.03

(0.98–1.07)

0.000

(0.004)

0.97

(0.94–1.01)

 High potency vs. others

0.91

(0.89–0.93)^‡

0.020

(0.002)^‡

0.92

(0.90–0.94)^‡

  Primary care clinic

Ref.

Ref.

Ref.

  District hospital

0.88

(0.83–0.93)^‡

−0.003

(0.006)

0.85

(0.81–0.90)^‡

  Regional hospital

0.78

(0.74–0.83)^‡

0.020

(0.006)^‡

0.82

(0.78–0.86)^‡

  Medical center

0.60

(0.56–0.63)^‡

0.070

(0.006)^‡

0.61

(0.58–0.64)^‡

  Other hospital

0.76

(0.71–0.82)^‡

0.033

(0.007)^‡

0.80

(0.75–0.86)^‡

 Eastern region

Ref.

Ref.

Ref.

 Taipei region

0.90

(0.86–0.94)^‡

0.037

(0.004)^‡

0.89

(0.86–0.93)^‡

 Northern region

0.87

(0.82–0.91)^‡

0.030

(0.005)^‡

0.87

(0.83–0.91)^‡

 Central region

1.00

(0.95–1.05)

−0.001

(0.004)

0.97

(0.92–1.01)

 Southern region

0.83

(0.79–0.87)^‡

0.044

(0.004)^‡

0.81

(0.77–0.84)^‡

 Kao-Ping region

0.84

(0.80–0.88)^‡

0.033

(0.004)^‡

0.84

(0.81–0.88)^‡

 Others (exclude all below)

Ref.

Ref.

Ref.

 Cardiovascular medicine

0.53

(0.50–0.56)^‡

0.109

(0.006)^‡

0.62

(0.59–0.65)^‡

 Cardiovascular surgery

0.53

(0.49–0.57)^‡

0.107

(0.007)^‡

0.65

(0.61–0.69)^‡

 Metabolism and Endocrinology

0.59

(0.55–0.63)^‡

0.115

(0.006)^‡

0.58

(0.55–0.62)^‡

 Neurology

0.68

(0.65–0.72)^‡

0.065

(0.006)^‡

0.80

(0.76–0.84)^‡

 Internal medicine

0.77

(0.73–0.82)^‡

0.040

(0.006)^‡

0.89

(0.85–0.93)^‡

 Family medicine

0.84

(0.77–0.92)^‡

0.020

(0.008)

0.92

(0.86–0.99)^†

 2006

Ref.

Ref.

Ref.

 2007

0.89

(0.86–0.91)^‡

0.024

(0.003)^‡

0.91

(0.89–0.94)^‡

 2008

0.83

(0.81–0.85)^‡

0.036

(0.003)^‡

0.86

(0.84–0.88)^‡

 2009

0.76

(0.74–0.78)^‡

0.048

(0.003)^‡

0.80

(0.78–0.82)^‡

 2010

0.72

(0.70–0.74)^‡

0.055

(0.003)^‡

0.75

(0.73–0.77)^‡

 2011

0.69

(0.67–0.71)^‡

0.059

(0.003)^‡

0.73

(0.71–0.75)^‡

 2012

0.49

(0.47–0.51)^‡

0.100

(0.003)^‡

0.69

(0.66–0.72)^‡