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Table 3 Adjusted odds ratios (95% confidence intervals) predicting medication non-adherence among 12,159 atrial fibrillation patients

From: Risk factors for medication non-adherence among atrial fibrillation patients

 

Atrial Fibrillation Patients

(n = 12,159)

Socio-demographics

Age group, years

  < 65

REF

 65–74

0.68 (0.55, 0.83)a

 75–84

0.67 (0.53, 0.84)a

  ≥ 85

0.86 (0.64, 1.16)

Gender

 Male

REF

 Female

0.97 (0.82, 1.15)

Race/Ethnicity

 Non-Hispanic White

REF

 Non-Hispanic Black

2.26 (1.73, 2.96)a

 Non-Hispanic Asian/Pacific Islander

1.59 (1.19, 2.13)b

 Hispanic

1.29 (0.98, 1.70)

 Other/Unknown

1.24 (0.89, 1.71)

Marital Status

 Married/Partner

REF

 Not Married/Partner

1.24 (1.05, 1.48)c

 Unknown

1.24 (0.53, 2.90)

Educational Attainment

 Less than High School

1.07 (0.78, 1.48)

 High School Graduate

1.01 (0.80, 1.29)

 Some College

1.07 (0.88, 1.29)

 Bachelor’s Degree or Higher

REF

 Unknown

1.35 (0.81, 2.27)

Household Income

 $25,000 or less

1.17 (0.89, 1.55)

 $25,001 – 50,000

1.00 (0.78, 1.28)

 $50,001 – 80,000

0.94 (0.73, 1.21)

 More than $80,000

REF

 Unknown

0.95 (0.74, 1.22)

Health Behaviors

Physical Activity (past month)

 None

1.57 (1.16, 2.13)b

 Low/Moderate

1.13 (0.93, 1.38)

 High

REF

 Unknown

1.81 (0.61, 5.37)

Cigarette Use (past year)

 Never

REF

 Former

0.98 (0.83, 1.16)

 Current

1.24 (0.92, 1.67)

 Unknown

1.00 (0.59, 1.70)

Alcohol Use (past year)

 Never

REF

 Former

1.69 (1.30, 2.20)a

 Current

1.91 (1.51, 2.43)a

 Unknown

1.36 (0.72, 2.58)

Self-Reported Health Status

Poor Physical Health (past month)

 0 days

REF

 1–7 days

1.43 (1.17, 1.75)a

 8–21 days

1.28 (0.96, 1.72)

 22–28 days

1.08 (0.47, 2.46)

  ≥ 29 days

1.17 (0.84, 1.61)

 Unknown

1.10 (0.83, 1.46)

Poor Mental Health (past month)

 0 days

REF

 1–7 days

1.31 (1.05, 1.63)c

 8–21 days

1.35 (0.99, 1.83)

 22–28 days

0.96 (0.40, 2.34)

  ≥ 29 days

1.44 (1.00, 2.06)c

 Unknown

1.78 (1.38, 2.31)a

Self-Rated Current Health

 Poor

0.80 (0.49, 1.32)

 Fair

0.94 (0.63, 1.40)

 Good

0.79 (0.54, 1.15)

 Very Good

0.94 (0.64, 1.37)

 Excellent

REF

 Unknown

1.20 (0.54, 2.69)

Sleep Affecting Daily Function (average)

 Never

REF

 Rarely

1.01 (0.82, 1.25)

 1–3 days/week

1.35 (1.05, 1.73)c

 4–6 days/week

1.46 (1.01, 2.11)c

 Almost every day

1.56 (1.19, 2.04)b

 Unknown

0.55 (0.24, 1.26)

Memory Decline (past 2–3 years)

 No

REF

 Yes

1.34 (1.13, 1.59)a

 Unknown

1.16 (0.89, 1.51)

Health Literacy

 Adequate

REF

 Inadequate

1.32 (1.09, 1.60)b

Medical History

Baby or Low-Dose Aspirin (past year; ≤100 mg/tablet)

 Did not use in the last 12 mo.

REF

 Did use in the last 12 mo.

1.21 (1.03, 1.42)c

 Unknown

1.01 (0.66, 1.56)

Aspirin or Aspirin-Product (past year; ≥325 mg/tablet)

 Did not use in the last 12 mo.

REF

 Did use in the last 12 mo.

1.03 (0.85, 1.25)

 Unknown

0.90 (0.64, 1.26)

Body Mass Index (kg/m2)

  < 25

REF

 25–30

1.07 (0.87, 1.31)

  ≥ 30

1.20 (0.96, 1.48)

 Unknown

0.87 (0.61, 1.24)

Charlson Comorbidity Index (past year)

 0

REF

 1

1.06 (0.86, 1.31)

 2

1.08 (0.84, 1.38)

  ≥ 3

0.77 (0.60, 1.00)c

Coronary Heart Disease

 No

REF

 Yes

1.01 (0.79, 1.28)

Chronic Heart Failure

 No

REF

 Yes

0.98 (0.80, 1.20)

Dementia

 No

REF

 Yes

0.76 (0.46, 1.24)

Depression

 No

REF

 Yes

0.96 (0.80, 1.16)

Diabetes Mellitus

 No

REF

 Yes

1.22 (1.01, 1.48)c

Hypertension

 No

REF

 Yes

0.72 (0.60, 0.87)a

Ischemic Stroke or Transient Ischemic Attack

 No

REF

 Yes

0.96 (0.68, 1.35)

  1. a < 0.001
  2. b < 0.01
  3. c < 0.05