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Table 3 Adjusted odds ratios (95% confidence intervals) predicting medication non-adherence among 12,159 atrial fibrillation patients

From: Risk factors for medication non-adherence among atrial fibrillation patients

  Atrial Fibrillation Patients
(n = 12,159)
Socio-demographics
Age group, years
  < 65 REF
 65–74 0.68 (0.55, 0.83)a
 75–84 0.67 (0.53, 0.84)a
  ≥ 85 0.86 (0.64, 1.16)
Gender
 Male REF
 Female 0.97 (0.82, 1.15)
Race/Ethnicity
 Non-Hispanic White REF
 Non-Hispanic Black 2.26 (1.73, 2.96)a
 Non-Hispanic Asian/Pacific Islander 1.59 (1.19, 2.13)b
 Hispanic 1.29 (0.98, 1.70)
 Other/Unknown 1.24 (0.89, 1.71)
Marital Status
 Married/Partner REF
 Not Married/Partner 1.24 (1.05, 1.48)c
 Unknown 1.24 (0.53, 2.90)
Educational Attainment
 Less than High School 1.07 (0.78, 1.48)
 High School Graduate 1.01 (0.80, 1.29)
 Some College 1.07 (0.88, 1.29)
 Bachelor’s Degree or Higher REF
 Unknown 1.35 (0.81, 2.27)
Household Income
 $25,000 or less 1.17 (0.89, 1.55)
 $25,001 – 50,000 1.00 (0.78, 1.28)
 $50,001 – 80,000 0.94 (0.73, 1.21)
 More than $80,000 REF
 Unknown 0.95 (0.74, 1.22)
Health Behaviors
Physical Activity (past month)
 None 1.57 (1.16, 2.13)b
 Low/Moderate 1.13 (0.93, 1.38)
 High REF
 Unknown 1.81 (0.61, 5.37)
Cigarette Use (past year)
 Never REF
 Former 0.98 (0.83, 1.16)
 Current 1.24 (0.92, 1.67)
 Unknown 1.00 (0.59, 1.70)
Alcohol Use (past year)
 Never REF
 Former 1.69 (1.30, 2.20)a
 Current 1.91 (1.51, 2.43)a
 Unknown 1.36 (0.72, 2.58)
Self-Reported Health Status
Poor Physical Health (past month)
 0 days REF
 1–7 days 1.43 (1.17, 1.75)a
 8–21 days 1.28 (0.96, 1.72)
 22–28 days 1.08 (0.47, 2.46)
  ≥ 29 days 1.17 (0.84, 1.61)
 Unknown 1.10 (0.83, 1.46)
Poor Mental Health (past month)
 0 days REF
 1–7 days 1.31 (1.05, 1.63)c
 8–21 days 1.35 (0.99, 1.83)
 22–28 days 0.96 (0.40, 2.34)
  ≥ 29 days 1.44 (1.00, 2.06)c
 Unknown 1.78 (1.38, 2.31)a
Self-Rated Current Health
 Poor 0.80 (0.49, 1.32)
 Fair 0.94 (0.63, 1.40)
 Good 0.79 (0.54, 1.15)
 Very Good 0.94 (0.64, 1.37)
 Excellent REF
 Unknown 1.20 (0.54, 2.69)
Sleep Affecting Daily Function (average)
 Never REF
 Rarely 1.01 (0.82, 1.25)
 1–3 days/week 1.35 (1.05, 1.73)c
 4–6 days/week 1.46 (1.01, 2.11)c
 Almost every day 1.56 (1.19, 2.04)b
 Unknown 0.55 (0.24, 1.26)
Memory Decline (past 2–3 years)
 No REF
 Yes 1.34 (1.13, 1.59)a
 Unknown 1.16 (0.89, 1.51)
Health Literacy
 Adequate REF
 Inadequate 1.32 (1.09, 1.60)b
Medical History
Baby or Low-Dose Aspirin (past year; ≤100 mg/tablet)
 Did not use in the last 12 mo. REF
 Did use in the last 12 mo. 1.21 (1.03, 1.42)c
 Unknown 1.01 (0.66, 1.56)
Aspirin or Aspirin-Product (past year; ≥325 mg/tablet)
 Did not use in the last 12 mo. REF
 Did use in the last 12 mo. 1.03 (0.85, 1.25)
 Unknown 0.90 (0.64, 1.26)
Body Mass Index (kg/m2)
  < 25 REF
 25–30 1.07 (0.87, 1.31)
  ≥ 30 1.20 (0.96, 1.48)
 Unknown 0.87 (0.61, 1.24)
Charlson Comorbidity Index (past year)
 0 REF
 1 1.06 (0.86, 1.31)
 2 1.08 (0.84, 1.38)
  ≥ 3 0.77 (0.60, 1.00)c
Coronary Heart Disease
 No REF
 Yes 1.01 (0.79, 1.28)
Chronic Heart Failure
 No REF
 Yes 0.98 (0.80, 1.20)
Dementia
 No REF
 Yes 0.76 (0.46, 1.24)
Depression
 No REF
 Yes 0.96 (0.80, 1.16)
Diabetes Mellitus
 No REF
 Yes 1.22 (1.01, 1.48)c
Hypertension
 No REF
 Yes 0.72 (0.60, 0.87)a
Ischemic Stroke or Transient Ischemic Attack
 No REF
 Yes 0.96 (0.68, 1.35)
  1. a < 0.001
  2. b < 0.01
  3. c < 0.05