Table 5 Contemporary Cohort (after 2010): Predictors of hospital readmission within 365 days of discharge
HR | 95% CI | p value | |
|---|---|---|---|
Demographics | |||
Age | 1.00 | (1.00 - 1.01) | 0.49 |
Female sex | 0.80 | (0.51 - 1.24) | 0.32 |
Dependent living | 0.90 | (0.64 - 1.26) | 0.53 |
Clinical Characteristics | |||
NYHA class | |||
I/II | reference | ||
III | 1.03 | (0.78 - 1.34) | 0.85 |
IV | 1.36 | (0.99 - 1.87) | 0.06 |
Frailty | 0.92 | (0.64 - 1.33) | 0.67 |
Cardiac comorbidities and interventions | |||
Atrial fibrillation | 1.29 | (1.02 - 1.63) | 0.04 |
Prior heart failure | 1.12 | (0.74 - 1.69) | 0.59 |
Prior myocardial infarction | 1.03 | (0.73 - 1.44) | 0.88 |
PCI | 1.17 | (0.84 - 1.64) | 0.35 |
CABG | 0.80 | (0.57 - 1.12) | 0.19 |
Medical comorbidities | |||
Diabetes | 0.97 | (0.78 - 1.19) | 0.74 |
Cerebrovascular disease | 0.75 | (0.48 - 1.17) | 0.21 |
Peripheral vascular disease | 1.38 | (1.12 - 1.70) | 0.003 |
Dementia | 1.32 | (0.56 - 3.08) | 0.53 |
Dialysis | 1.75 | (1.18 - 2.59) | 0.01 |
Lung disease | 1.15 | (0.66 - 1.98) | 0.62 |
Liver disease | 1.58 | (0.22 - 11.2) | 0.65 |
Peptic ulcer disease | 1.52 | (1.01 - 2.27) | 0.04 |
History of bleeding | 1.09 | (0.72 - 1.66) | 0.69 |
Laboratory markers | |||
eGFR | 1.00 | (0.99 - 1.00) | 0.19 |
Hemoglobin | 0.99 | (0.99 - 1.00) | <0.001 |
Echocardiographic findings | |||
Left ventricular dysfunction | 0.78 | (0.59 - 1.04) | 0.09 |
Procedural characteristics | |||
Urgent procedure | 1.08 | (0.64 - 1.84) | 0.77 |
Valve in valve | 0.76 | (0.59 - 0.99) | 0.04 |
Self-expandable prosthesis | 0.94 | (0.82 - 1.07) | 0.36 |
Non-femoral vascular access site | 1.38 | (1.05 - 1.81) | 0.02 |
TAVR year | 0.92 | (0.82 - 1.04) | 0.18 |
Procedural complications | |||
Stroke | 1.27 | (0.80 - 2.02) | 0.32 |
Permanent pacemaker | 1.43 | (0.92 - 2.22) | 0.11 |
Delirium | 1.26 | (0.87 - 1.85) | 0.23 |
Bleeding, vascular complication or transfusion | 1.38 | (1.13 - 1.68) | 0.001 |
Echocardiographic findings post-TAVR | |||
Mitral regurgitation | |||
Nil/trace | reference | ||
Mild | 1.23 | (0.86 - 1.76) | 0.26 |
Moderate/Severe | 1.29 | (0.89 - 1.86) | 0.17 |
Aortic regurgitation | |||
Nil/trace | reference | ||
Mild | 1.24 | (1.05 - 1.47) | 0.01 |
Moderate/Severe | 1.35 | (0.95 - 1.93) | 0.10 |
Previous health resource utilization | |||
Hospitalization 30 days before TAVR | 1.09 | (0.88 - 1.35) | 0.44 |
Transitional care factors | |||
Rehabilitation | 1.34 | (1.12 - 1.61) | 0.002 |
Home care | 1.12 | (0.85 - 1.48) | 0.42 |
Family physician follow-up | 0.93 | (0.69 - 1.25) | 0.63 |
Cardiologist follow-up | 1.29 | (1.05 - 1.58) | 0.02 |