Fig. 1

Pedigree of the CHD family and sequence results of the TAB2 mutation. a All sampled subjects in the pedigree are identified by Roman numerals below the symbol. Arabic numbers denote each individual in a generation. Open symbols, unaffected; filled symbols, affected; symbols with a diagonal line, deceased subjects; squares, male; circles, female; diamond, fetus with unknown sex; arrow, the proband. b Sequence chromatogram indicates a C-to-G transition of nucleotide 466