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Fig. 3 | BMC Cardiovascular Disorders

Fig. 3

From: Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells

Fig. 3

Ticagrelor and clopidogrel inhibit the LPS-induced changes in cell apoptosis, cycle and migration ability. a: HUVECs were incubated with the indicated compounds for 16 h, and then, cell viability was determined by CCK-8 assays. b-c: Flow cytometric analysis of APC/7-AAD staining was used to analyze apoptosis in HUVECs following incubation with the indicated compounds for 16 h. d-e: After HUVECs were incubated with the indicated compounds for 16 h, cell migration was assessed using a transwell assay, and cells were stained using hexamethylpararosaniline solution. f-g: HUVECs were incubated with the indicated compounds for 16 h and stained with propidium iodide. DNA content was analyzed by flow cytometry (n = 3; ns, not significant, p > 0.05; *, p < 0.05; **, p < 0.01; and ***, p < 0.001)

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BMC Cardiovascular Disorders

ISSN: 1471-2261

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