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Table 1 Comparison of demographics and biochemical parameters of subjects among the four groups

From: Association of Klotho gene polymorphism with hypertension and coronary artery disease in an Iranian population

Variables

H-Tens

(N = 60)

CAD + H-Tens

(N = 95)

CAD

(N = 61)

Ctrl

(N = 70)

P-value

Age, years

54.5 ± 9.4

58.2 ± 9.5

57.2 ± 9.6

52.9 ± 11.1

0.003*

Sex (m/f)

23/37

59/36

44/17

33/37

0.001*

BMI (kg/m2)

26.9 ± 5.3

24.6 ± 4.5

24.1 ± 4.2

25.1 ± 4.7

0.016*

FBS (mg/dl)

95.1 ± 12.0

91.9 ± 10.2

92.2 ± 10.5

94.6 ± 12.6

0.182

TG (mg/dl)

118.9 ± 59.2

114.6 ± 70.8

109.1 ± 47.0

104. ± 36.0

0.840

TC (mg/dl)

142. ± 32.4

138.1 ± 39.2

145.0 ± 42.6

140.9 ± 41.5

0.634

HDL-c (mg/dl)

38.3 ± 9.3

37.4 ± 11.3

38.9 ± 12.1

40.7 ± 10.0

0.276

LDL-c (mg/dl)

78.6 ± 30.9

77.6 ± 33.2

84.2 ± 35.4

78.3 ± 37.4

0.656

Na (mmol/l)

139.4 ± 3.1

139.3 ± 3.0

140.3 ± 2.6

138.9 ± 3.0

0.143

K (mmol/l)

4.3 ± 0.4

4.2 ± 0.4

4.4 ± 0.4

4.3 ± 0.4

0.101

Cr (mg/dl)

0.9 ± 0.2

1.0 ± 0.2

1.1 ± 0.1

1.0 ± 0.2

<0.001*

Urea (mg/dl)

34.9 ± 9.8

36.8 ± 11.7

36.0 ± 10.3

34.2 ± 12.7

0.514

  1. H-Tens = Hypertension; CAD + H-Tens = Coronary artery disease and hypertension; CAD = Coronary artery disease; Ctrl = Control. Values are presented as mean ± SD. The differences of continuous variables among the study groups were analyzed using one-way analysis of variance (ANOVA)/Kruskal-Wallis with post-hoc Tukey/Mann-Whitney U tests. *Significant difference (P<0.05)