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Table 3 Comparison of serum MMP9 and TLR4 levels between AAD and control group stratified by cardiovascular risk factors

From: Serum levels of matrix metalloproteinase 9 and toll-like receptor 4 in acute aortic dissection: a case-control study

Variables

 

Control

AAD

Control

AAD

MMP9(ng/ml)

MMP9(ng/ml)

p vs. Control

TLR4(ng/ml)

TLR4(ng/ml)

p vs. Control

Age

<60y

143.91 ± 117.89

378.40 ± 92.86

< 0.001

4.43 ± 2.67

12.39 ± 9.89

< 0.001

≥60y

299.93 ± 111.27

348.23 ± 139.12

0.008

7.84 ± 2.78

13.81 ± 9.94

0.001

Gender

male

233.88 ± 140.40

364.87 ± 121.92

< 0.001

6.18 ± 3.30

13.74 ± 11.17

< 0.001

female

215.25 ± 132.76

361.55 ± 106.59

< 0.001

6.61 ± 2.99

11.16 ± 4.27

< 0.001

Smoking

Yes

218.50 ± 143.35

354.69 ± 121.82

< 0.001

6.04 ± 2.64

14.68 ± 11.66

< 0.001

No

235.95 ± 135.17

369.87 ± 115.49

< 0.001

6.45 ± 3.55

12.05 ± 8.54

< 0.001

Drinking

Yes

232.46 ± 144.07

361.91 ± 121.77

< 0.001

6.11 ± 2.99

12.42 ± 10.17

0.002

No

226.51 ± 134.70

365.14 ± 116.22

< 0.001

6.42 ± 3.38

13.42 ± 9.79

< 0.001

Hypertension

Yes

245.21 ± 131.57

348.85 ± 123.60

< 0.001

6.93 ± 3.54

11.24 ± 6.92

< 0.001

No

215.52 ± 142.98

404.40 ± 89.71

< 0.001

5.75 ± 2.83

17.95 ± 14.28

< 0.001

Diabetes

Yes

207.47 ± 147.81

360.06 ± 126.11

0.003

7.66 ± 4.05

13.76 ± 11.84

0.019

No

231.77 ± 137.38

366.15 ± 113.67

< 0.001

6.11 ± 3.07

12.69 ± 8.73

< 0.001

Hyperlipidemia

Yes

272.67 ± 130.16

404.97 ± 87.75

< 0.001

6.99 ± 3.12

15.56 ± 9.49

< 0.001

No

213.57 ± 138.25

350.34 ± 123.45

< 0.001

6.04 ± 3.23

12.24 ± 9.94

< 0.001