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Table 5 Subgroup analyses for stroke

From: Association of sodium intake and major cardiovascular outcomes: a dose-response meta-analysis of prospective cohort studies

Factor

Subgroup

RR and 95% CI

P value

Heterogeneity (%)

P value for heterogeneity

P value between subgroups

Publication year

Before 2010

1.09 (0.95–1.24)

0.211

54.5

0.086

0.248

2010 or after

1.14 (0.96–1.35)

0.127

58.2

0.067

Sample size

≥ 10,000

1.03 (0.99–1.07)

0.181

0.0

0.537

0.020

<  10,000

1.18 (1.02–1.36)

0.029

46.5

0.096

Percentage male (%)

≥ 60.0

1.03 (0.99–1.07)

0.181

0.0

0.537

0.020

<  60.0

1.18 (1.02–1.36)

0.029

46.5

0.096

Assessment of exposure

FFQ

1.19 (0.95–1.50)

0.125

76.0

0.016

0.503

24 h urine collection

1.08 (0.96–1.21)

0.190

36.8

0.176

Follow-up duration (years)

≥ 10.0

1.15 (0.97–1.37)

0.116

72.4

0.012

0.453

<  10.0

1.08 (0.98–1.20)

0.136

18.2

0.300

Adjusted BMI

Yes

1.10 (1.01–1.19)

0.029

53.7

0.035

–

No

–

–

–

–

Adjusted smoking

Yes

1.13 (1.00–1.28)

0.048

60.2

0.020

0.865

No

1.05 (0.97–1.14)

0.236

–

–

Adjusted alcohol

Yes

1.14 (0.99–1.31)

0.072

66.2

0.011

0.744

No

1.06 (0.98–1.14)

0.174

0.0

0.636

Adjusted Previous CVD

Yes

1.09 (0.99–1.20)

0.074

64.4

0.038

0.395

No

1.10 (0.91–1.32)

0.317

49.7

0.114

Adjusted DM

Yes

1.14 (0.99–1.31)

0.072

66.2

0.011

0.744

No

1.06 (0.98–1.14)

0.174

0.0

0.636

Adjusted PA

Yes

1.11 (1.01–1.22)

0.026

64.6

0.015

0.892

No

1.03 (0.82–1.29)

0.811

0.0

0.326

Adjusted potassium

Yes

1.04 (0.96–1.13)

0.309

0.0

0.396

0.963

No

1.16 (1.02–1.33)

0.029

65.2

0.013

  1. *BMI body mass index, CI confidence interval, CVD cardiovascular disease, DM diabetes mellitus, FFQ food frequency questionnaire, PA physical activity, RR relative risk