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Table 7 The rs7396366 polymorphism and other risk factors in 1-, 2-, and 3-vessel lesion patients compared with controls

From: A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population

Variables

One-vessel disease

Two-vessel disease

Three-vessel disease

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

Age

–

<.001

–

<.001

–

<.001

Sex

1.17 (0.81–1.67)

.406

2.42 (1.47–3.99)

<.001

2.49 (1.47–4.20)

<.001

BMI

–

.703

–

.343

–

.727

Smoking

1.00 (0.67–1.50)

.997

1.39 (0.84–2.30)

.230

1.62 (0.97–2.71)

.073

Hypertension

1.86 (1.26–2.75)

.002

2.48 (1.43–4.30)

.001

1.67 (0.99–2.85)

.054

Total cholesterol (mmol/L)

–

.848

–

.215

–

.018

T2DM

1.47 (0.93–2.33)

.115

2.01 (1.15–3.50)

.018

3.85 (2.26–6.56)

<.001

Fasting plasma glucose (mmol/L)

–

.040

–

.066

–

.023

Rs7396366(TT)

1.63 (0.90–2.96)

.112

1.58 (0.74–3.38)

.280

2.86 (1.45–5.65)

.005

Rs7396366 (TT vs. GG)

1.68(0.91–3.10)

.103

2.37 (1.05–5.35)

.048

2.48 (1.23–5.01)

.014

  1. Abbreviations: OR odds ratio, CI confidence interval
  2. Age, BMI, total cholesterol and fasting plasma glucose were compared using the Student t test. Other data were compared using the χ2-test
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BMC Cardiovascular Disorders

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