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Table 5 Clinical characteristics in controls and CAD cases with different number of vessel lesions

From: A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population

Variables Number of vessels involved P
0 (n = 372) 1 (n = 173) 2 (n = 85) 3 (n = 77)
Age (years) 58.11 ± 11.53 65.67 ± 10.81 66.65 ± 11.29 68.90 ± 10.95 <.001
Sex (male) 175 (47.0) 88 (50.9) 58 (68.2) 53 (68.8) <.001
BMI (kg/m2) 25.09 ± 4.39 25.25 ± 3.57 25.64 ± 3.93 24.84 ± 3.87 .356
Smoking, n (%) 101 (27.2) 47 (27.2) 29 (34.1) 29 (37.7) .190
Hypertension, n (%) 217 (58.3) 125 (72.3) 66 (77.6) 54 (79.1) <.001
Total cholesterol(mmol/L) 4.64 ± 1.55 4.66 ± 1.21 4.40 ± 1.35 4.19 ± 1.11 .037
T2DM, n (%) 58 (15.6) 37 (21.4) 23 (27.1) 32 (41.6) <.001
Fasting plasma glucose (mmol/L) 5.70 ± 1.62 6.02 ± 1.87 6.06 ± 1.65 6.16 ± 1.61 .039
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 GG 206 (55.4) 89 (51.4) 30 (35.3) 43 (55.8) .009
 GT 137 (36.8) 63 (36.4) 45 (52.9) 19 (24.7) .003
 TT 29 (7.8) 21 (12.1) 10 (11.8) 15 (19.5) .018
  1. Abbreviations: OR odds ratio, CI confidence interval
  2. Age, BMI, Total cholesterol and fasting plasma glucose are expressed as the mean ± SD and were compared using the one-way ANOVA. Other data are expressed as frequencies and percentages and were compared using the χ2-test