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Table 5 Clinical characteristics in controls and CAD cases with different number of vessel lesions

From: A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population

Variables

Number of vessels involved

P

0 (n = 372)

1 (n = 173)

2 (n = 85)

3 (n = 77)

Age (years)

58.11 ± 11.53

65.67 ± 10.81

66.65 ± 11.29

68.90 ± 10.95

<.001

Sex (male)

175 (47.0)

88 (50.9)

58 (68.2)

53 (68.8)

<.001

BMI (kg/m2)

25.09 ± 4.39

25.25 ± 3.57

25.64 ± 3.93

24.84 ± 3.87

.356

Smoking, n (%)

101 (27.2)

47 (27.2)

29 (34.1)

29 (37.7)

.190

Hypertension, n (%)

217 (58.3)

125 (72.3)

66 (77.6)

54 (79.1)

<.001

Total cholesterol(mmol/L)

4.64 ± 1.55

4.66 ± 1.21

4.40 ± 1.35

4.19 ± 1.11

.037

T2DM, n (%)

58 (15.6)

37 (21.4)

23 (27.1)

32 (41.6)

<.001

Fasting plasma glucose (mmol/L)

5.70 ± 1.62

6.02 ± 1.87

6.06 ± 1.65

6.16 ± 1.61

.039

Rs7396366

 GG

206 (55.4)

89 (51.4)

30 (35.3)

43 (55.8)

.009

 GT

137 (36.8)

63 (36.4)

45 (52.9)

19 (24.7)

.003

 TT

29 (7.8)

21 (12.1)

10 (11.8)

15 (19.5)

.018

  1. Abbreviations: OR odds ratio, CI confidence interval
  2. Age, BMI, Total cholesterol and fasting plasma glucose are expressed as the mean ± SD and were compared using the one-way ANOVA. Other data are expressed as frequencies and percentages and were compared using the χ2-test