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Table 1 Comparison of the Demographic and Baseline Characteristics of unmatched and matched AKI and non-AKI groups

From: Role of elevated red cell distribution width on acute kidney injury patients after cardiac surgery

 

Unmatched Cohort (n = 10,274)

P-value

Matched Cohort (n = 3146)

P-value

Non-AKI group (n = 6909)

AKI group(n = 3364)

Non-AKI group (n = 1573)

AKI group (n = 1573)

Age (years)

51.7 ± 14.0

56.8 ± 12.3

<  0.001

54.6 ± 12.0

54.4 ± 12.1

0.782

Male, sex

3584 (51.9%)

2233 (66.6%)

<  0.001

966 (61.4%)

913 (58.0%)

0.059

Comorbidities

 Hypertension

1748 (25.3%)

1177 (35%)

<  0.001

422 (26.8%)

457 (29.1%)

0.177

 DM

628 (9.1%)

386 (11.5%)

<  0.001

139 (8.8%)

151 (9.6%)

0.498

Creatinine, μmol/L

75.7 ± 20.6

83.6 ± 29.5

<  0.001

77.1 ± 17.3

77.8 ± 19.7

0.325

 eGFR

93.0 ± 22.1

87.3 ± 25.3

<  0.001

91.5 ± 20.7

91.0 ± 24.1

0.566

 BUN

6.1 ± 2.1

7.0 ± 2.8

<  0.001

6.2 ± 1.9

6.3 ± 1.8

0.063

 Albumin baseline

40.6 ± 3.3

40.1 ± 3.3

<  0.001

40.0 ± 3.4

39.9 ± 3.5

0.162

 Hemoglobin, g/dL

136.5 ± 14.6

137.3 ± 15.9

0.005

134.7 ± 17.0

133.6 ± 18.7

0.093

 WBC, 1000/μL

6.4 ± 2.0

6.5 ± 2.2

0.033

6.4 ± 2.4

6.4 ± 2.0

0.532

 Elevated RDW, %

0.3 (0.0, 0.6)

0.5 (0.1,1.0)

<  0.001

0.3 (0.0,0.7)

0.5 (0.1,1.1)

< 0.001

 Platelet fl

188.8 ± 56.7

177.3 ± 56.4

<  0.001

189.2 ± 62.1

178.2 ± 58.7

< 0.001

BMI, kg/m2

22.9 ± 3.0

23.5 ± 3.2

0.013

22.6 ± 3.2

23.3 ± 3.7

< 0.001

 SUA

351.0 ± 104.7

394.0 ± 138.6

<  0.001

355.6 ± 101.0

377.0 ± 108.6

< 0.001

NYHA functional class

 I-II

3420 (49.5%)

1370 (40.7)

<  0.001

755 (48.0%)

610 (38.8%)

< 0.001

 III-IV

3489 (50.5%)

1995 (59.3)

<  0.001

818 (52.0%)

963 (61.2%)

< 0.001

LVEF%

62.4 ± 8.3

61.4 ± 19.3

0.071

62.1 ± 8.1

61.3 ± 9.4

0.092

CPB time (min)

81.0 (65.0, 105.0)

101.0 (78.0, 128.0)

<  0.001

80.5 (65.0,105.0)

99.0 (78.0,126.0)

< 0.001

ACC time (min)

48.0 (36.0, 67.0)

58.0 (43.0, 78.0)

<  0.001

48.0 (37.0,67.0)

55.0 (41.0,78.0)

< 0.001

Pre-operative coronary angiography n (%)

2543 (36.8)

1528 (45.4)

< 0.001

690 (43.9%)

617 (39.2%)

0.009

Time interval between coronary angiogram and cardiac surgery (days)

4 (2, 6)

4 (2, 6)

0.212

3 (2,6)

3 (2,6)

0.981

  1. AKI acute kidney injury, BMI body mass index, DM diabetes mellitus, WBC white blood cell, RDW red cell distribution width, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate SUA serum uric acid, NYHA New York Heart Association, LVEF left ventricular ejection fraction, CPB cardiopulmonary bypass, ACC Aortic cross-clamp