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Table 1 Comparison of the Demographic and Baseline Characteristics of unmatched and matched AKI and non-AKI groups

From: Role of elevated red cell distribution width on acute kidney injury patients after cardiac surgery

  Unmatched Cohort (n = 10,274) P-value Matched Cohort (n = 3146) P-value
Non-AKI group (n = 6909) AKI group(n = 3364) Non-AKI group (n = 1573) AKI group (n = 1573)
Age (years) 51.7 ± 14.0 56.8 ± 12.3 <  0.001 54.6 ± 12.0 54.4 ± 12.1 0.782
Male, sex 3584 (51.9%) 2233 (66.6%) <  0.001 966 (61.4%) 913 (58.0%) 0.059
Comorbidities
 Hypertension 1748 (25.3%) 1177 (35%) <  0.001 422 (26.8%) 457 (29.1%) 0.177
 DM 628 (9.1%) 386 (11.5%) <  0.001 139 (8.8%) 151 (9.6%) 0.498
Creatinine, μmol/L 75.7 ± 20.6 83.6 ± 29.5 <  0.001 77.1 ± 17.3 77.8 ± 19.7 0.325
 eGFR 93.0 ± 22.1 87.3 ± 25.3 <  0.001 91.5 ± 20.7 91.0 ± 24.1 0.566
 BUN 6.1 ± 2.1 7.0 ± 2.8 <  0.001 6.2 ± 1.9 6.3 ± 1.8 0.063
 Albumin baseline 40.6 ± 3.3 40.1 ± 3.3 <  0.001 40.0 ± 3.4 39.9 ± 3.5 0.162
 Hemoglobin, g/dL 136.5 ± 14.6 137.3 ± 15.9 0.005 134.7 ± 17.0 133.6 ± 18.7 0.093
 WBC, 1000/μL 6.4 ± 2.0 6.5 ± 2.2 0.033 6.4 ± 2.4 6.4 ± 2.0 0.532
 Elevated RDW, % 0.3 (0.0, 0.6) 0.5 (0.1,1.0) <  0.001 0.3 (0.0,0.7) 0.5 (0.1,1.1) < 0.001
 Platelet fl 188.8 ± 56.7 177.3 ± 56.4 <  0.001 189.2 ± 62.1 178.2 ± 58.7 < 0.001
BMI, kg/m2 22.9 ± 3.0 23.5 ± 3.2 0.013 22.6 ± 3.2 23.3 ± 3.7 < 0.001
 SUA 351.0 ± 104.7 394.0 ± 138.6 <  0.001 355.6 ± 101.0 377.0 ± 108.6 < 0.001
NYHA functional class
 I-II 3420 (49.5%) 1370 (40.7) <  0.001 755 (48.0%) 610 (38.8%) < 0.001
 III-IV 3489 (50.5%) 1995 (59.3) <  0.001 818 (52.0%) 963 (61.2%) < 0.001
LVEF% 62.4 ± 8.3 61.4 ± 19.3 0.071 62.1 ± 8.1 61.3 ± 9.4 0.092
CPB time (min) 81.0 (65.0, 105.0) 101.0 (78.0, 128.0) <  0.001 80.5 (65.0,105.0) 99.0 (78.0,126.0) < 0.001
ACC time (min) 48.0 (36.0, 67.0) 58.0 (43.0, 78.0) <  0.001 48.0 (37.0,67.0) 55.0 (41.0,78.0) < 0.001
Pre-operative coronary angiography n (%) 2543 (36.8) 1528 (45.4) < 0.001 690 (43.9%) 617 (39.2%) 0.009
Time interval between coronary angiogram and cardiac surgery (days) 4 (2, 6) 4 (2, 6) 0.212 3 (2,6) 3 (2,6) 0.981
  1. AKI acute kidney injury, BMI body mass index, DM diabetes mellitus, WBC white blood cell, RDW red cell distribution width, BUN blood urea nitrogen, eGFR estimated glomerular filtration rate SUA serum uric acid, NYHA New York Heart Association, LVEF left ventricular ejection fraction, CPB cardiopulmonary bypass, ACC Aortic cross-clamp