Table 2 Cost inputs
Variable | Value | Variance | Distribution and coefficients for probabilistic sensitivity analysis | Source |
|---|---|---|---|---|
Cost of Barostim implant procedure, € | 3628 | 1814–5442 | – | G-DRG 901D 2013, LOS = 2 days, cost of implant was subtracted |
Cost of battery replacement procedure, € | 1808 | 904–2712 | – | G-DRG F17B 2013, LOS = 2 days, cost of implant was subtracted |
Cost of pre- and post-implant physician visits, € | 68 | 34–102 | – | EBM 13542 (1 visit), EBM 07212 (2 visits) |
Cost of full Barostim system, € | 21,000 | 15,000–24,000 | – | CVRx Inc. |
Cost of Barostim battery, € | 15,000 | 10,000–17,000 | – | CVRx Inc. |
Cost of short-term complications, € | 3056 | 1528–4584 | – | G-DRG 901D 2013. The difference between 2 and 5-day LOS. It was assumed that complication will lead to prolongation of hospital stay |
Cost of long-term complications, € | 0 | 0–100 | – | Assumption |
Battery life, years | 6 | 3–6 | – | CVRx Inc. |
Percentage of patients being hospitalized with stay in intensive care unit | 7.2% | – | – | Yao 2007 [20] |
Percentage of patients being hospitalized with stay in coronary care unit | 25.6% | – | – | |
Percentage of patients being hospitalized with CABG performed | 0.3% | – | – | |
Percentage of patients being hospitalized with PTCA performed | 0.2% | – | – | |
Percentage of patients being hospitalized with heart transplantation performed | 2.6% | – | – | |
Percentage of patients being hospitalized with no procedure performed | 62.3% | – | – | |
Cost of hospitalization with stay in intensive care unit, € | 5005 | 2502–7507 | – | G-DRG code F62A 2013 |
Cost of hospitalization with stay in coronary care unit, € | 5004 | 2502–7507 | – | G-DRG code F62A 2013 |
Cost of hospitalization with CABG performed, € | 15,056 | 7528–22,584 | – | G-DRG code F06E |
Cost of hospitalization with PTCA performed, € | 3793 | 1896–5689 | – | G-DRG code F56B plus ZE101 |
Cost of hospitalization with heart transplantation performed, € | 86,337 | 43,169–129,507 | – | G-DRG code A05B 2013 |
Cost of hospitalization with no procedure performed, € | 2740 | 1370–4110 | – | G-DRG code F62B 2013 |
Yearly cost of routine management NYHA I, € | 516 | 258–1031 | Gamma (α = 1;λ = 516) | Biermann 2012 [22] |
Yearly cost of routine management NYHA II, € | 910 | 455–1821 | Gamma (α = 1;λ = 910) | |
Yearly cost of routine management NYHA III, € | 900 | 450–1800 | Gamma (α = 1;λ = 900) | |
Yearly cost of routine management NYHA IV, € | 967 | 484–1935 | Gamma (α = 1;λ = 967) |